AIMC Topic: Machine Learning

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Evaluation of risk factors for thromboembolic events in multiple myeloma patients using multiple machine learning models.

Medicine
Venous thromboembolic events (VTE) is a frequent complication in multiple myeloma (MM) patients, raising mortality. This study aims to use machine learning to identify VTE risk factors in MM, helping to pinpoint high-risk individuals for better clini...

Machine learning algorithm approach to complete blood count can be used as early predictor of COVID-19 outcome.

Journal of leukocyte biology
Although the SARS-CoV-2 infection has established risk groups, identifying biomarkers for disease outcomes is still crucial to stratify patient risk and enhance clinical management. Optimal efficacy of COVID-19 antiviral medications relies on early a...

[Prediction of depression symptoms in seniors and analysis of influencing factors based on explainable machine learning].

Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi
This study aims to construct a machine learning model to predict depression symptoms in the elderly and analyze the key influencing factors of depression in the elderly using the shapley additive interpretation (SHAP) method. Based on entries from ...

The Harms of Class Imbalance Corrections for Machine Learning Based Prediction Models: A Simulation Study.

Statistics in medicine
INTRODUCTION: Risk prediction models are increasingly used in healthcare to aid in clinical decision-making. In most clinical contexts, model calibration (i.e., assessing the reliability of risk estimates) is critical. Data available for model develo...

Tracking vigilance fluctuations in real-time: a sliding-window heart rate variability-based machine-learning approach.

Sleep
STUDY OBJECTIVES: Heart rate variability (HRV)-based machine learning models hold promise for real-world vigilance evaluation, yet their real-time applicability is limited by lengthy feature extraction times and reliance on subjective benchmarks. Thi...

Using minor variant genomes and machine learning to study the genome biology of SARS-CoV-2 over time.

Nucleic acids research
In infected individuals, viruses are present as a population consisting of dominant and minor variant genomes. Most databases contain information on the dominant genome sequence. Since the emergence of SARS-CoV-2 in late 2019, variants have been sele...

Probabilistic and machine-learning methods for predicting local rates of transcription elongation from nascent RNA sequencing data.

Nucleic acids research
Rates of transcription elongation vary within and across eukaryotic gene bodies. Here, we introduce new methods for predicting elongation rates from nascent RNA sequencing data. First, we devise a probabilistic model that predicts nucleotide-specific...

Building a cancer risk and survival prediction model based on social determinants of health combined with machine learning: A NHANES 1999 to 2018 retrospective cohort study.

Medicine
The occurrence and progression of cancer is a significant focus of research worldwide, often accompanied by a prolonged disease course. Concurrently, researchers have identified that social determinants of health (SDOH) (employment status, family inc...

Machine learning model using immune indicators to predict outcomes in early liver cancer.

World journal of gastroenterology
BACKGROUND: Patients with early-stage hepatocellular carcinoma (HCC) generally have good survival rates following surgical resection. However, a subset of these patients experience recurrence within five years post-surgery.

Differentiating between renal medullary and clear cell renal carcinoma with a machine learning radiomics approach.

The oncologist
BACKGROUND: The objective of this study was to develop and validate a radiomics-based machine learning (ML) model to differentiate between renal medullary carcinoma (RMC) and clear cell renal carcinoma (ccRCC).