AIMC Topic: Machine Learning

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SMR-guided molecular subtyping and machine learning model reveals novel prognostic biomarkers and therapeutic targets in non-small cell lung adenocarcinoma.

Scientific reports
Non-small cell lung adenocarcinoma (LUAD) is a markedly heterogeneous disease, with its underlying molecular mechanisms and prognosis prediction presenting ongoing challenges. In this study, we integrated data from multiple public datasets, including...

Machine learning identified novel players in lipid metabolism, endosomal trafficking, and iron metabolism of the ALS spinal cord.

Scientific reports
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease affecting motor neurons. Although genes causing familial cases have been identified, those of sporadic ALS, which occupies the majority of patients, are still elusive. In this s...

Combination of gray level features with deep transfer learning for copra classification using machine learning and neural networks.

Scientific reports
Copra (dried coconut) is used for oil production and raw materials for its by-products. Traditionally, Coconuts are halved and sun-dried in the field. Fumigation using sulphur is employed in the industry to maintain its colour and prevent microbial g...

A hybrid explainable model based on advanced machine learning and deep learning models for classifying brain tumors using MRI images.

Scientific reports
Brain tumors present a significant global health challenge, and their early detection and accurate classification are crucial for effective treatment strategies. This study presents a novel approach combining a lightweight parallel depthwise separabl...

Qwen-2.5 Outperforms Other Large Language Models in the Chinese National Nursing Licensing Examination: Retrospective Cross-Sectional Comparative Study.

JMIR medical informatics
BACKGROUND: Large language models (LLMs) have been proposed as valuable tools in medical education and practice. The Chinese National Nursing Licensing Examination (CNNLE) presents unique challenges for LLMs due to its requirement for both deep domai...

Combining machine learning and single-cell sequencing to identify key immune genes in sepsis.

Scientific reports
This research aimed to identify novel indicators for sepsis by analyzing RNA sequencing data from peripheral blood samples obtained from sepsis patients (n = 23) and healthy controls (n = 10). 5148 differentially expressed genes were identified using...

A robust transfer learning approach for high-dimensional linear regression to support integration of multi-source gene expression data.

PLoS computational biology
Transfer learning aims to integrate useful information from multi-source datasets to improve the learning performance of target data. This can be effectively applied in genomics when we learn the gene associations in a target tissue, and data from ot...

The advantages of lexicon-based sentiment analysis in an age of machine learning.

PloS one
Assessing whether texts are positive or negative-sentiment analysis-has wide-ranging applications across many disciplines. Automated approaches make it possible to code near unlimited quantities of texts rapidly, replicably, and with high accuracy. C...

Developing and validating a machine learning model to predict multidrug-resistant -related septic shock.

Frontiers in immunology
BACKGROUND: Multidrug-resistant Klebsiella pneumoniae (MDR-KP) infections pose a significant global healthcare challenge, particularly due to the high mortality risk associated with septic shock. This study aimed to develop and validate a machine lea...

The potential role of machine learning and deep learning in differential diagnosis of Alzheimer's disease and FTD using imaging biomarkers: A review.

The neuroradiology journal
IntroductionThe prevalence of neurodegenerative diseases has significantly increased, necessitating a deeper understanding of their symptoms, diagnostic processes, and prevention strategies. Frontotemporal dementia (FTD) and Alzheimer's disease (AD) ...