AIMC Topic: Male

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Data-driven identification of key predictors of uncontrolled hypertension: A cross-sectional study.

PloS one
Uncontrolled hypertension (HTN) increases the risk of adverse health events. This study aimed to identify key predictors of uncontrolled HTN in 1,308 Mexican adults with a prior diagnosis of HTN who were undergoing pharmacological treatment. We utili...

The public's perceptions and attitudes of male nursing postgraduate professional identity on Chinese social media: Qualitative study based on machine learning.

PloS one
BACKGROUND: Professional identity plays a critical role in the career development of male postgraduate nursing students, particularly in contexts where gender imbalance and social stereotypes persist.

FAM46B inhibits CS-induced oxidative stress and ferroptosis in bronchial epithelial cells via KLHL24.

International immunopharmacology
BACKGROUND: Chronic obstructive pulmonary disease (COPD), mainly caused by cigarette smoke (CS), is a global health concern. Ferroptosis is recognized as a key driver of COPD progression, yet its underlying mechanisms are unclear. This study aimed to...

KPNA2 expression as a biomarker for immunosuppressive microenvironment predicting response to TKI and immunotherapy in metastatic renal cell carcinoma.

European journal of pharmacology
BACKGROUND: Immunotherapy (IO) combined with tyrosine kinase inhibitors (TKI) are now first-line therapy for advanced renal cell carcinoma (RCC), though reliable predictive biomarkers remain elusive. Recent evidence demonstrates that karyopherin α2 s...

Cognitive prediction using regional connectivities and network biomarkers in Alzheimer's disease.

Neuroscience
Achieving a deep understanding of brain mechanisms requires multi-scale perspectives to capture the architecture of complex networks. In this study, we focused on patients with cognitive impairment and constructed individual brain networks from neuro...

AlzFormer: Video-based space-time attention model for early diagnosis of Alzheimer's disease.

Neuroscience
Early and accurate Alzheimer's disease (AD) diagnosis is critical for effective intervention, but it is still challenging due to neurodegeneration's slow and complex progression. Recent studies in brain imaging analysis have highlighted the crucial r...

Potential of Proteomics in Forensic Phenotyping: A Focus on Biological Sex Estimation.

Journal of proteome research
Forensic DNA analysis is well established for phenotyping, providing valuable investigative leads. Proteomics, the large-scale study of proteins, is emerging as a complementary tool to DNA analysis, particularly for enhancing the evidential value of ...

UCP2 is identified as a therapeutic target for abdominal aortic aneurysm by comprehensive bioinformatic analysis and experimental validation.

Biochemical and biophysical research communications
Abdominal aortic aneurysm (AAA) is a potentially life-threatening vascular condition that currently lacks effective pharmacological treatment. The disease is strongly associated with chronic inflammation, where immune cells like macrophages play a cr...

Machine learning prediction of clinical pregnancy in endometriosis patients following fresh IVF/ICSI-ET.

European journal of medical research
BACKGROUND: Fresh embryo transfer reduces waiting time and minimizes embryo cryodamage for endometriosis (EM) patients. The current prediction models for fresh embryo transfer outcomes in EM primarily rely on logistic regression, with limited applica...

Comparing supervised machine learning algorithms for the prediction of partial arterial pressure of oxygen during craniotomy.

BMC medical informatics and decision making
BACKGROUND AND OBJECTIVES: Brain tissue oxygenation is usually inferred from arterial partial pressure of oxygen (paO), which is in turn often inferred from pulse oximetry measurements or other non-invasive proxies. Our aim was to evaluate the feasib...