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Discovery of phenotypic networks from genotypic association studies with application to obesity.

International journal of data mining and bioinformatics
Genome-wide Association Studies (GWAS) have resulted in many discovered risk variants for several obesity-related traits. However, before clinical relevance of these discoveries can be achieved, molecular or physiological mechanisms of these risk var...

Neural network models - a novel tool for predicting the efficacy of growth hormone (GH) therapy in children with short stature.

Neuro endocrinology letters
INTRODUCTION: The leading method for prediction of growth hormone (GH) therapy effectiveness are multiple linear regression (MLR) models. Best of our knowledge, we are the first to apply artificial neural networks (ANN) to solve this problem. For ANN...

Acute appendicitis diagnosis using artificial neural networks.

Technology and health care : official journal of the European Society for Engineering and Medicine
BACKGROUND: Artificial neural networks is one of pattern analyzer method which are rapidly applied on a bio-medical field.

Do post-stroke patients benefit from robotic verticalization? A pilot-study focusing on a novel neurophysiological approach.

Restorative neurology and neuroscience
BACKGROUND: Tilt-table equipped with the dynamic foot-support (ERIGO) and the functional electric stimulation could be a safe and suitable device for stabilization of vital signs, increasing patient's motivation for further recovery, decreasing the d...

Fuzzy linguistic prediction model for sinoatrial node field potential analysis in acute hyperglycemia environment.

Bio-medical materials and engineering
The objective of this study is to build a fuzzy linguistic prediction model (FLPM) for analyzing the actuation duration of acute hyperglycemia to sinoatrial node field potential. The field potential was recorded using microelectrode arrays (MEA). The...

Improved walking ability with wearable robot-assisted training in patients suffering chronic stroke.

Bio-medical materials and engineering
Wearable robotic devices provide safe and intensive rehabilitation, enabling repeated motions for motor function recovery in stroke patients. The aim of this small case series was to demonstrate the training effects of a three-week robotic leg orthos...

Classification of focal liver lesions on ultrasound images by extracting hybrid textural features and using an artificial neural network.

Bio-medical materials and engineering
This paper focuses on the improvement of the diagnostic accuracy of focal liver lesions by quantifying the key features of cysts, hemangiomas, and malignant lesions on ultrasound images. The focal liver lesions were divided into 29 cysts, 37 hemangio...

Nonholonomic mobile system control by combining EEG-based BCI with ANFIS.

Bio-medical materials and engineering
Motor imagery EEG-based BCI has advantages in the assistance of human control of peripheral devices, such as the mobile robot or wheelchair, because the subject is not exposed to any stimulation and suffers no risk of fatigue. However, the intensive ...

Identification of Conversion from Normal Elderly Cognition to Alzheimer's Disease using Multimodal Support Vector Machine.

Journal of Alzheimer's disease : JAD
Alzheimer's disease (AD) is one of the most serious progressive neurodegenerative diseases among the elderly, therefore the identification of conversion to AD at the earlier stage has become a crucial issue. In this study, we applied multimodal suppo...