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Machine learning-based prediction model for omental metastasis in right-sided colon cancer patients: a retrospective multicenter study.

International journal of colorectal disease
PURPOSE: Current diagnostic modalities lack sufficient sensitivity for detecting omental metastasis (OM), often underestimating metastatic burden. Unlike traditional statistical model, machine learning (ML) model is designed to detect subtle variable...

Classifying complex multimorbidity using latent class analysis and machine learning to generate insights into clustering of mental and cardiometabolic conditions.

PloS one
Machine learning techniques earn higher accuracy and robustness in multimorbidity prediction at this moment in time. Among various forms of multimorbidity, complex multimorbidity, especially the intersection of cardiometabolic disorders and mental he...

Human asymmetries in AI art: Syntax and writing direction effects on agent position in AI-generated images.

PloS one
The present study investigates positional patterns in visual representations generated by two artificial intelligence (AI) models in response to textual prompts describing interactions between two animate entities. The primary objective is to assess ...

Prediction of disability levels and research on nursing economic costs for elderly people in China.

PloS one
This study aims to solve the problem of the shortage of professional nursing staff and the inability of the quality of nursing services to meet the needs of the elderly. Therefore, a longitudinal research type was adopted for long-term tracking and o...

Machine Learning Identifies FLNA as a Key Molecular Target Regulating Neuronal Apoptosis after Spinal Cord Injury.

Journal of molecular neuroscience : MN
Spinal cord injury (SCI), a traumatic type of central nervous system injury, is closely associated with neuronal apoptosis. However, the specific biomarkers and regulatory mechanisms of neuronal apoptosis in SCI patients remain unclear. In this study...

Multi-marker discovery for mild cognitive impairment in metabolomics using machine learning with a global surrogate model via partial least squares.

Metabolomics : Official journal of the Metabolomic Society
INTRODUCTION: Dementia can be prevented through early intervention; hence, there is an urgent need for biomarkers to help diagnose mild cognitive impairment (MCI).

Performance of the pediatric index of mortality (PIM-3) in a Moroccan PICU: challenges in resource-limited settings.

European journal of pediatrics
UNLABELLED: Prognostic scores such as the Pediatric Index of Mortality (PIM-3) are widely used to estimate mortality risk in PICUs, yet their performance in low- and middle-income countries (LMICs) remains uncertain. We aimed to evaluate the predicti...

Electroencephalography source-space functional connectivity reveals frequency-specific brain network dysfunctions in obsessive-compulsive disorder.

Progress in neuro-psychopharmacology & biological psychiatry
BACKGROUND: Obsessive-compulsive disorder (OCD) is characterized by disruptions in large-scale brain networks. However, the role of high-frequency neural synchrony in these abnormalities remains unclear. Elucidating frequency-specific alterations may...

The association between estimated glucose disposal rate and the prevalence and mortality of chronic kidney disease: a cross-sectional study with linked mortality follow-up.

European journal of medical research
BACKGROUND: Metabolic disorders represented by insulin resistance (IR) are at risk of chronic kidney disease (CKD). Estimated glucose disposal rate (eGDR) reflects IR. The relationship between eGDR and CKD was unclear. This study aimed at discussing ...

Development of a consensus molecular classifier for pancreatic ductal adenocarcinoma.

Genome medicine
BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) presents a significant challenge, with a 5-year survival rate of approximately 10%. Tumor heterogeneity contributes to the limited effectiveness of treatments. Several tumor and stroma molecular cla...