AIMC Topic: Metabolic Diseases

Clear Filters Showing 11 to 20 of 32 articles

Identification of immune-related mitochondrial metabolic disorder genes in septic shock using bioinformatics and machine learning.

Hereditas
PURPOSE: Mitochondria are involved in septic shock and inflammatory response syndrome, which severely affects the life security of patients. It is necessary to recognize and explore the immune-mitochondrial genes in septic shock.

Mesocorticolimbic and Cardiometabolic Diseases-Two Faces of the Same Coin?

International journal of molecular sciences
The risk behaviors underlying the most prevalent chronic noncommunicable diseases (NCDs) encompass alcohol misuse, unhealthy diets, smoking and sedentary lifestyle behaviors. These are all linked to the altered function of the mesocorticolimbic (MCL)...

Digital twins and artificial intelligence in metabolic disease research.

Trends in endocrinology and metabolism: TEM
Digital twin technology is emerging as a transformative paradigm for personalized medicine in the management of chronic conditions. In this article, we explore the concept and key characteristics of a digital twin and its applications in chronic non-...

Engineering novel scaffolds for specific HDAC11 inhibitors against metabolic diseases exploiting deep learning, virtual screening, and molecular dynamics simulations.

International journal of biological macromolecules
The prevalence of metabolic diseases is increasing at a frightening rate year by year. The burgeoning development of deep learning enables drug design to be more efficient, selective, and structurally novel. The critical relevance of Histone deacetyl...

Towards precision cardiometabolic prevention: results from a machine learning, semi-supervised clustering approach in the nationwide population-based ORISCAV-LUX 2 study.

Scientific reports
Given the rapid increase in the incidence of cardiometabolic conditions, there is an urgent need for better approaches to prevent as many cases as possible and move from a one-size-fits-all approach to a precision cardiometabolic prevention strategy ...

Ranking of a wide multidomain set of predictor variables of children obesity by machine learning variable importance techniques.

Scientific reports
The increased prevalence of childhood obesity is expected to translate in the near future into a concomitant soaring of multiple cardio-metabolic diseases. Obesity has a complex, multifactorial etiology, that includes multiple and multidomain potenti...

Systems metabolomics: from metabolomic snapshots to design principles.

Current opinion in biotechnology
Metabolomics is a rapidly expanding technology that finds increasing application in a variety of fields, form metabolic disorders to cancer, from nutrition and wellness to design and optimization of cell factories. The integration of metabolic snapsh...

Application of Machine Learning to Identify Clustering of Cardiometabolic Risk Factors in U.S. Adults.

Diabetes technology & therapeutics
The aim of this study is to compare some machine learning methods with traditional statistical parametric analyses using logistic regression to investigate the relationship of risk factors for diabetes and cardiovascular (cardiometabolic risk) for U...

Using Health Chatbots for Behavior Change: A Mapping Study.

Journal of medical systems
This study conducts a mapping study to survey the landscape of health chatbots along three research questions: What illnesses are chatbots tackling? What patient competences are chatbots aimed at? Which chatbot technical enablers are of most interest...