Journal of biomolecular structure & dynamics
Jul 14, 2023
Marfan syndrome (MFS) is a hereditary disease with high mortality. This study aimed to explore peripheral blood potential markers and underlying mechanisms in MFS via a series bioinformatics and machine learning analysis. First, we downloaded two MFS...
MicroRNAs have a significant role in the emergence of various human disorders. Consequently, it is essential to understand the existing interactions between miRNAs and diseases, as this will help scientists better study and comprehend the diseases' b...
BACKGROUND: The discovery of a saliva-based micro–ribonucleic acid (miRNA) signature for endometriosis in 2022 opened up new perspectives for early and noninvasive diagnosis of the disease. The 109-miRNA saliva signature is the product of miRNA bioma...
MicroRNAs (miRNA) are small, non-coding regulatory molecules whose effective alteration might result in abnormal gene manifestation in the downstream pathway of their target. miRNA gene variants can impact miRNA transcription, maturation, or target s...
BACKGROUND: Deep learning techniques are gaining momentum in medical research. Colorectal adenoma (CRA) is a precancerous lesion that may develop into colorectal cancer (CRC) and its etiology and pathogenesis are unclear. This study aims to identify ...
Computer methods and programs in biomedicine
Jan 27, 2023
BACKGROUND AND OBJECTIVE: Integrating multi-omics data for the comprehensive analysis of the biological processes in human diseases has become one of the most challenging tasks of bioinformatics. Deep learning (DL) algorithms have recently become one...
International journal of molecular sciences
Jan 18, 2023
Aberrant miRNA expression has been associated with a large number of human diseases. Therefore, targeting miRNAs to regulate their expression levels has become an important therapy against diseases that stem from the dysfunction of pathways regulated...
The binding of microRNAs (miRNAs) to their target sites is a complex process, mediated by the Argonaute (Ago) family of proteins. The prediction of miRNA:target site binding is an important first step for any miRNA target prediction algorithm. To dat...
Artificial neural networks have revolutionized electronic computing. Similarly, molecular networks with neuromorphic architectures may enable molecular decision-making on a level comparable to gene regulatory networks. Non-enzymatic networks could in...
Computational and mathematical methods in medicine
Sep 23, 2022
Acute, chronic myocarditis as myocardial localized or diffuse inflammation lesions is usually involving cardiac function in patients with severe adverse outcomes such as heart failure, sudden death, and no unified, but its pathogenesis clinical is ma...
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