AIMC Topic: Middle Aged

Clear Filters Showing 1061 to 1070 of 17155 articles

Stacking ensemble learning models diagnose pulmonary infections using host transcriptome data from metatranscriptomics.

Scientific reports
The prompt diagnosis of pulmonary infections with unknown etiology in patients in severe condition remains a challenge due to the lack of rapid and effective diagnostic methods. While metatranscriptomic sequencing offers a powerful approach, its clin...

A study on the effectiveness of machine learning models for hepatitis prediction.

Scientific reports
Hepatitis continues to be a major global health challenge, leading to high morbidity and mortality rates. Despite advances in diagnosis and treatment, early prediction of hepatitis outcomes remains an essential area for improvement. This study seeks ...

Machine learning model for early diagnosis of breast cancer based on PiRNA expression with CA153.

Scientific reports
PIWI-interacting RNAs (piRNAs) have been implicated in the biological processes of various cancers. This study aimed to investigate the diagnostic potential of circulating piRNAs in breast cancer (BC) using machine learning (ML) frameworks. A serum t...

A comprehensive deep learning approach to improve enchondroma detection on X-ray images.

Scientific reports
An enchondroma is a benign neoplasm of mature hyaline cartilage that proliferates from the medullary cavity toward the cortical bone. This results in the formation of a significant endogenous mass within the medullary cavity. Although enchondromas ar...

Machine learning-based prediction model for post-stroke cerebral-cardiac syndrome: a risk stratification study.

Scientific reports
Cerebral-cardiac syndrome (CCS) is a severe cardiac complication following acute ischemic stroke, often associated with adverse outcomes. This study developed and validated a machine learning (ML) model to predict CCS using clinical, laboratory, and ...

Enhancing classification of a large lower-limb motor imagery EEG dataset for BCI in knee pain patients.

Scientific data
Chronic knee osteoarthritis pain significantly impacts patients' quality of life and motor function. While motor imagery (MI)-based brain-computer interface (BCI) systems have shown promise in rehabilitation, their application to lower-limb condition...

Evaluating the Prototype of a Clinical Decision Support System in Primary Care: Qualitative Study.

JMIR formative research
BACKGROUND: General practitioners are confronted with a wide variety of diseases and sometimes diagnostic uncertainty. Clinical decision support systems could be valuable to improve diagnosis, but existing tools are not adapted to the requirements an...

Multimodal analysis of cell-free DNA enhances differentiation of early-stage breast cancer from benign lesions and healthy individuals.

BMC biology
BACKGROUND: Breast cancer (BC) remains the second leading cause of cancer-related mortality among women worldwide. Liquid biopsy based on circulating tumor DNA (ctDNA) offers a promising noninvasive approach for early detection; however, differentiat...

Predicting post-liver transplantation mortality: a retrospective cohort study on risk factor identification and prognostic nomogram construction.

European journal of medical research
BACKGROUND: To identify risk factors for post-transplant mortality and develop a machine learning-integrated prognostic tool to optimise clinical decision-making in liver transplantation (LT) recipients.

Optimizing timing and cost-effective use of plasma biomarkers in Alzheimer's disease.

Alzheimer's research & therapy
BACKGROUND AND OBJECTIVES: Early and cost-effective identification of amyloid positivity is crucial for Alzheimer's disease (AD) diagnosis. While amyloid PET is the gold standard, plasma biomarkers such as phosphorylated tau 217 (pTau217) provide a p...