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Heterogeneous blood pressure treatment effects on cognitive decline in type 2 diabetes: A machine learning analysis of a randomized clinical trial.
Diabetes, obesity & metabolism
Dec 26, 2024
AIM: We aimed to identify the characteristics of patients with diabetes who can derive cognitive benefits from intensive blood pressure (BP) treatment using machine learning methods.
Predicting benefit from PARP inhibitors using deep learning on H&E-stained ovarian cancer slides.
European journal of cancer (Oxford, England : 1990)
Dec 26, 2024
PURPOSE: Ovarian cancer patients with a Homologous Recombination Deficiency (HRD) often benefit from polyadenosine diphosphate-ribose polymerase (PARP) inhibitor maintenance therapy after response to platinum-based chemotherapy. HR status is currentl...
Comparison of population pharmacokinetic modeling and machine learning approaches for predicting voriconazole trough concentrations in critically ill patients.
International journal of antimicrobial agents
Dec 26, 2024
BACKGROUND: Despite the widespread use of voriconazole in antifungal treatment, its high pharmacokinetic and pharmacodynamic variability may lead to suboptimal efficacy, especially in intensive care unit (ICU) patients. Machine learning (ML), an arti...
AI-Enhanced Healthcare: Integrating ChatGPT-4 in ePROs for Improved Oncology Care and Decision-Making: A Pilot Evaluation.
Current oncology (Toronto, Ont.)
Dec 26, 2024
BACKGROUND: Since 2023, ChatGPT-4 has been impactful across several sectors including healthcare, where it aids in medical information analysis and education. Electronic patient-reported outcomes (ePROs) play a crucial role in monitoring cancer patie...
Pathomics-based machine learning models for predicting pathological complete response and prognosis in locally advanced rectal cancer patients post-neoadjuvant chemoradiotherapy: insights from two independent institutional studies.
BMC cancer
Dec 26, 2024
BACKGROUND: Accurate prediction of pathological complete response (pCR) and disease-free survival (DFS) in locally advanced rectal cancer (LARC) patients undergoing neoadjuvant chemoradiotherapy (NCRT) is essential for formulating effective treatment...
Diagnosis of intracranial aneurysms by computed tomography angiography using deep learning-based detection and segmentation.
Journal of neurointerventional surgery
Dec 26, 2024
BACKGROUND: Detecting and segmenting intracranial aneurysms (IAs) from angiographic images is a laborious task.
Association between serum endocan levels and organ failure in hospitalized patients with cirrhosis.
PloS one
Dec 26, 2024
BACKGROUND & AIMS: Acute-on-chronic liver failure is a syndrome characterized by organ failure and high short-term mortality. The lack of reliable biomarkers for the early detection of acute-on-chronic liver failure is a significant challenge. Endoth...
Machine learning-based pipeline for automated intracerebral hemorrhage and drain detection, quantification, and classification in non-enhanced CT images (NeuroDrAIn).
PloS one
Dec 26, 2024
BACKGROUND AND PURPOSE: External drainage represents a well-established treatment option for acute intracerebral hemorrhage. The current standard of practice includes post-operative computer tomography imaging, which is subjectively evaluated. The im...
Correlation between individual thigh muscle volume and grip strength in relation to sarcopenia with automated muscle segmentation.
PloS one
Dec 26, 2024
INTRODUCTION: Grip strength serves as a significant marker for diagnosing and assessing sarcopenia, particularly in elderly populations. The study aims to explore the relationship between individual thigh muscle volumes and grip strength, leveraging ...
The predictive value of heparin-binding protein for bacterial infections in patients with severe polytrauma.
PloS one
Dec 26, 2024
INTRODUCTION: Heparin-binding protein is an inflammatory factor with predictive value for sepsis and participates in the inflammatory response through antibacterial effects, chemotaxis, and increased vascular permeability. The role of heparin-binding...
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