AIMC Topic: Middle Aged
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Activated cancer-associated fibroblasts correlate with poor survival and decreased lymphocyte infiltration in infiltrative type distal cholangiocarcinoma.
Scientific reports
Jul 1, 2025
Cancer-associated fibroblasts promote tumor progression through growth facilitation, invasion, and immune evasion. This study investigated the impact of activated cancer-associated fibroblasts (aCAFs) on survival outcomes, immune response, and molecu...
Comparison of AI chatbot predicted and realworld survival outcomes in hepatocellular carcinoma.
Scientific reports
Jul 1, 2025
This study compares survival predictions made by an artificial intelligence (AI) based chatbot with real-world data in hepatocellular carcinoma (HCC) patients. It aims to evaluate the reliability and accuracy of AI technologies in HCC prognosis. A re...
Evaluation of MRI-based synthetic CT for lumbar degenerative disease: a comparison with CT.
Scientific reports
Jul 1, 2025
Patients with lumbar degenerative disease typically undergo preoperative MRI combined with CT scans, but this approach introduces additional ionizing radiation and examination costs. To compare the effectiveness of MRI-based synthetic CT (sCT) in dis...
Metabolomic biomarkers could be molecular clocks in timing stroke onset.
Scientific reports
Jul 1, 2025
The preferred treatment for acute ischaemic stroke (AIS) is intravenous thrombolysis (IVT) administered within 4.5 hours (h) of symptom onset. This study aimed to identify metabolomic biomarkers for distinguishing AIS patients within 4.5 h of symptom...
Beyond accuracy: a framework for evaluating algorithmic bias and performance, applied to automated sleep scoring.
Scientific reports
Jul 1, 2025
Recent advancements in artificial intelligence (AI) have significantly improved sleep-scoring algorithms, bringing their performance close to the theoretical limit of approximately 80%, which aligns with inter-scorer agreement levels. While this sugg...
AI-based CT assessment of 3117 vertebrae reveals significant sex-specific vertebral height differences.
Scientific reports
Jul 1, 2025
Predicting vertebral height is complex due to individual factors. AI-based medical imaging analysis offers new opportunities for vertebral assessment. Thereby, these novel methods may contribute to sex-adapted nomograms and vertebral height predictio...
A novel UHPLC-HRMS method for simultaneous determination of 20 amino metabolites and proteins in lymphoma patients' cells and serum.
Scientific reports
Jul 1, 2025
Highly sensitive and selective monitoring of amino metabolites such as glutamine, arginine, tryptophan and related proteins played significant roles in early diagnosis and warning of lymphoma. But those limited abundance and lacked chromophore group ...
Brain structural features with functional priori to classify Parkinson's disease and multiple system atrophy using diagnostic MRI.
Scientific reports
Jul 1, 2025
Clinical two-dimensional (2D) MRI data has seen limited application in the early diagnosis of Parkinson's disease (PD) and multiple system atrophy (MSA) due to quality limitations, yet its diagnostic and therapeutic potential remains underexplored. T...
Radiomics analysis based on dynamic contrast-enhanced MRI for predicting early recurrence after hepatectomy in hepatocellular carcinoma patients.
Scientific reports
Jul 1, 2025
This study aimed to develop a machine learning model based on Magnetic Resonance Imaging (MRI) radiomics for predicting early recurrence after curative surgery in patients with hepatocellular carcinoma (HCC).A retrospective analysis was conducted on ...
Machine learning and transformer models for prediction of postoperative pneumonia risk in patients with lower limb fractures.
Scientific reports
Jul 1, 2025
Postoperative pneumonia, a prevalent complication arising from lower limb fracture surgery, can significantly prolong hospitalization periods and elevate mortality rates. Consequently, early prevention and identification of this condition are crucial...
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