AIMC Topic: Middle Aged

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Prognostic enrichment for early-stage Huntington's disease: An explainable machine learning approach for clinical trial.

NeuroImage. Clinical
BACKGROUND: In Huntington's disease clinical trials, recruitment and stratification approaches primarily rely on genetic load, cognitive and motor assessment scores. They focus less on in vivo brain imaging markers, which reflect neuropathology well ...

Application of machine learning to predict in-hospital mortality after transcatheter mitral valve repair.

Surgery
INTRODUCTION: Transcatheter mitral valve repair offers a minimally invasive treatment option for patients at high risk for traditional open repair. We sought to develop dynamic machine-learning risk prediction models for in-hospital mortality after t...

Non-invasive prediction of axillary lymph node dissection exemption in breast cancer patients post-neoadjuvant therapy: A radiomics and deep learning analysis on longitudinal DCE-MRI data.

Breast (Edinburgh, Scotland)
PURPOSE: In breast cancer (BC) patients with clinical axillary lymph node metastasis (cN+) undergoing neoadjuvant therapy (NAT), precise axillary lymph node (ALN) assessment dictates therapeutic strategy. There is a critical demand for a precise meth...

Accuracy and time efficiency of a novel deep learning algorithm for Intracranial Hemorrhage detection in CT Scans.

La Radiologia medica
PURPOSE: To evaluate a deep learning-based pipeline using a Dense-UNet architecture for the assessment of acute intracranial hemorrhage (ICH) on non-contrast computed tomography (NCCT) head scans after traumatic brain injury (TBI).

Deep learning based clinical target volumes contouring for prostate cancer: Easy and efficient application.

Journal of applied clinical medical physics
BACKGROUND: Radiotherapy has been crucial in prostate cancer treatment. However, manual segmentation is labor intensive and highly variable among radiation oncologists. In this study, a deep learning based automated contouring model is constructed fo...

A multicenter study on deep learning for glioblastoma auto-segmentation with prior knowledge in multimodal imaging.

Cancer science
A precise radiotherapy plan is crucial to ensure accurate segmentation of glioblastomas (GBMs) for radiation therapy. However, the traditional manual segmentation process is labor-intensive and heavily reliant on the experience of radiation oncologis...

Family history of cancer and lung cancer: Utility of big data and artificial intelligence for exploring the role of genetic risk.

Lung cancer (Amsterdam, Netherlands)
OBJECTIVES: Lung Cancer (LC) is a multifactorial disease for which the role of genetic susceptibility has become increasingly relevant. Our aim was to use artificial intelligence (AI) to analyze differences between patients with LC based on family hi...

Clinical application of convolutional neural network lung nodule detection software: An Australian quaternary hospital experience.

Journal of medical imaging and radiation oncology
INTRODUCTION: Early-stage lung cancer diagnosis through detection of nodules on computed tomography (CT) remains integral to patient survivorship, promoting national screening programmes and diagnostic tools using artificial intelligence (AI) convolu...

Unraveling the impact of therapeutic drug monitoring via machine learning for patients with sepsis.

Cell reports. Medicine
Clinical studies investigating the benefits of beta-lactam therapeutic drug monitoring (TDM) among critically ill patients are hindered by small patient groups, variability between studies, patient heterogeneity, and inadequate use of TDM. Accordingl...

The impact of differential pricing subject on consumer behavior.

BMC psychology
The escalating use of artificial intelligence in marketing significantly impacts all aspects of consumer life. This research, grounded in attribution theory and S-O-R theory, employs scenario-based experimental methods to simulate two distinct purcha...