Machine learning (ML) classification of myocardial scarring in cardiac MRI is often hindered by limited explainability, particularly with convolutional neural networks (CNNs). To address this, we developed One Match (OM), an algorithm that builds on ...
Although iron is an essential element for vital body functions, iron overload (IO) is accompanied by significant cellular damage due to its accumulation within organs. Thus, early diagnosis and accurate identification of the affected organs are criti...
BACKGROUND: Cardiac magnetic resonance imaging (CMR) provides critical pathological information, such as scars and edema, which are vital for diagnosing myocardial infarction (MI). However, due to the limited pathological information in single-sequen...
Molecular & cellular proteomics : MCP
Mar 18, 2025
Protein compartmentalization to distinctive subcellular niches is critical for cardiac function and homeostasis. Here, we employed a rapid and robust workflow based on differential centrifugal-based fractionation with mass spectrometry-based proteomi...
Small (Weinheim an der Bergstrasse, Germany)
Feb 5, 2025
Democratizing biomarker testing at the point-of-care requires innovations that match laboratory-grade sensitivity and precision in an accessible format. Here, high-sensitivity detection of cardiac troponin I (cTnI) is demonstrated through innovations...
Assessing myocardial viability is crucial for managing ischemic heart disease. While late gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) is the gold standard for viability evaluation, it has limitations, including contraindicati...
BACKGROUND: Cardiac magnetic resonance (CMR) imaging is an important diagnostic tool for diagnosis of cardiac amyloidosis (CA). However, discrimination of CA from other etiologies of myocardial disease can be challenging.
Biomedical physics & engineering express
Nov 29, 2024
This paper introduces a deep learning method for myocardial strain analysis while also evaluating the efficacy of the method across a public and a private dataset for cardiac pathology discrimination.We measure the global and regional myocardial stra...
The international journal of cardiovascular imaging
Nov 7, 2024
Myocarditis, characterized by inflammation of the myocardial tissue, presents substantial risks to cardiovascular functionality, potentially precipitating critical outcomes including heart failure and arrhythmias. This investigation primarily aims to...
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