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Neoplasm Invasiveness

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Quantitative assessment of cancer cell morphology and motility using telecentric digital holographic microscopy and machine learning.

Cytometry. Part A : the journal of the International Society for Analytical Cytology
The noninvasive, fast acquisition of quantitative phase maps using digital holographic microscopy (DHM) allows tracking of rapid cellular motility on transparent substrates. On two-dimensional surfaces in vitro, MDA-MB-231 cancer cells assume several...

Deep Learning based Radiomics (DLR) and its usage in noninvasive IDH1 prediction for low grade glioma.

Scientific reports
Deep learning-based radiomics (DLR) was developed to extract deep information from multiple modalities of magnetic resonance (MR) images. The performance of DLR for predicting the mutation status of isocitrate dehydrogenase 1 (IDH1) was validated in ...

Neoadjuvant endocrine treatment in early breast cancer: An overlooked alternative?

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
During the last decade neoadjuvant endocrine therapy (NET) has moved from being reserved for elderly and frail non-chemotherapy candidates to a primary systemic modality in selected patients with hormone sensitive breast cancer. Neoadjuvant hormonal ...

Modulatory role of garlicin in migration and invasion of intrahepatic cholangiocarcinoma via PI3K/AKT pathway.

International journal of clinical and experimental pathology
Increasing evidences have indicated the role of garlicin in inhibiting the progression of various tumors including glioma, pulmonary carcinoma and pancreatic carcinoma, via mediating cell apoptosis or cell cycle. The regulatory effect and related mol...

Minimization of curative surgery for treatment of early cervical cancer: a review.

Japanese journal of clinical oncology
Surgery is effective and useful for curative treatment of patients with early invasive cervical cancer, yet minimization of surgical procedures provides many additional advantages for patients. Because the mean age of patients diagnosed with cervical...