AIMC Topic: Observer Variation

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Optimized generation of high-resolution phantom images using cGAN: Application to quantification of Ki67 breast cancer images.

PloS one
In pathology, Immunohistochemical staining (IHC) of tissue sections is regularly used to diagnose and grade malignant tumors. Typically, IHC stain interpretation is rendered by a trained pathologist using a manual method, which consists of counting e...

Automated classification of celiac disease during upper endoscopy: Status quo and quo vadis.

Computers in biology and medicine
A large amount of digital image material is routinely captured during esophagogastroduodenoscopies but, for the most part, is not used for confirming the diagnosis process of celiac disease which is primarily based on histological examination of biop...

Deep Learning Algorithm for Auto-Delineation of High-Risk Oropharyngeal Clinical Target Volumes With Built-In Dice Similarity Coefficient Parameter Optimization Function.

International journal of radiation oncology, biology, physics
PURPOSE: Automating and standardizing the contouring of clinical target volumes (CTVs) can reduce interphysician variability, which is one of the largest sources of uncertainty in head and neck radiation therapy. In addition to using uniform margin e...

Classification of breast cancer in ultrasound imaging using a generic deep learning analysis software: a pilot study.

The British journal of radiology
OBJECTIVE: To train a generic deep learning software (DLS) to classify breast cancer on ultrasound images and to compare its performance to human readers with variable breast imaging experience.

Fully automated, deep learning segmentation of oxygen-induced retinopathy images.

JCI insight
Oxygen-induced retinopathy (OIR) is a widely used model to study ischemia-driven neovascularization (NV) in the retina and to serve in proof-of-concept studies in evaluating antiangiogenic drugs for ocular, as well as nonocular, diseases. The primary...

A method to combine target volume data from 3D and 4D planned thoracic radiotherapy patient cohorts for machine learning applications.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
BACKGROUND AND PURPOSE: The gross tumour volume (GTV) is predictive of clinical outcome and consequently features in many machine-learned models. 4D-planning, however, has prompted substitution of the GTV with the internal gross target volume (iGTV)....

Reliability of an automatic classifier for brain enlarged perivascular spaces burden and comparison with human performance.

Clinical science (London, England : 1979)
In the brain, enlarged perivascular spaces (PVS) relate to cerebral small vessel disease (SVD), poor cognition, inflammation and hypertension. We propose a fully automatic scheme that uses a support vector machine (SVM) to classify the burden of PVS ...