AIMC Topic: Phenotype

Clear Filters Showing 901 to 910 of 922 articles

Electronic Health Record Phenotypes for Precision Medicine: Perspectives and Caveats From Treatment of Breast Cancer at a Single Institution.

Clinical and translational science
Precision medicine is at the forefront of biomedical research. Cancer registries provide rich perspectives and electronic health records (EHRs) are commonly utilized to gather additional clinical data elements needed for translational research. Howev...

Discovering Pediatric Asthma Phenotypes on the Basis of Response to Controller Medication Using Machine Learning.

Annals of the American Thoracic Society
RATIONALE: Pediatric asthma has variable underlying inflammation and symptom control. Approaches to addressing this heterogeneity, such as clustering methods to find phenotypes and predict outcomes, have been investigated. However, clustering based o...

Graph-based semi-supervised learning with genomic data integration using condition-responsive genes applied to phenotype classification.

Journal of the American Medical Informatics Association : JAMIA
OBJECTIVE: Data integration methods that combine data from different molecular levels such as genome, epigenome, transcriptome, etc., have received a great deal of interest in the past few years. It has been demonstrated that the synergistic effects ...

DeepPhe: A Natural Language Processing System for Extracting Cancer Phenotypes from Clinical Records.

Cancer research
Precise phenotype information is needed to understand the effects of genetic and epigenetic changes on tumor behavior and responsiveness. Extraction and representation of cancer phenotypes is currently mostly performed manually, making it difficult t...

Plant phenomics: an overview of image acquisition technologies and image data analysis algorithms.

GigaScience
The study of phenomes or phenomics has been a central part of biology. The field of automatic phenotype acquisition technologies based on images has seen an important advance in the last years. As with other high-throughput technologies, it addresses...

Deep machine learning provides state-of-the-art performance in image-based plant phenotyping.

GigaScience
In plant phenotyping, it has become important to be able to measure many features on large image sets in order to aid genetic discovery. The size of the datasets, now often captured robotically, often precludes manual inspection, hence the motivation...

An integrative machine learning strategy for improved prediction of essential genes in Escherichia coli metabolism using flux-coupled features.

Molecular bioSystems
Prediction of essential genes helps to identify a minimal set of genes that are absolutely required for the appropriate functioning and survival of a cell. The available machine learning techniques for essential gene prediction have inherent problems...