AIMC Topic: Predictive Value of Tests

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Deep Learning-Based Algorithm for Detecting Aortic Stenosis Using Electrocardiography.

Journal of the American Heart Association
Background Severe, symptomatic aortic stenosis (AS) is associated with poor prognoses. However, early detection of AS is difficult because of the long asymptomatic period experienced by many patients, during which screening tools are ineffective. The...

Brain morphological changes in hypokinetic dysarthria of Parkinson's disease and use of machine learning to predict severity.

CNS neuroscience & therapeutics
BACKGROUND: Up to 90% of patients with Parkinson's disease (PD) eventually develop the speech and voice disorder referred to as hypokinetic dysarthria (HD). However, the brain morphological changes associated with HD have not been investigated. Moreo...

Improved Prediction of Surgical Resectability in Patients with Glioblastoma using an Artificial Neural Network.

Scientific reports
In managing a patient with glioblastoma (GBM), a surgeon must carefully consider whether sufficient tumour can be removed so that the patient can enjoy the benefits of decompression and cytoreduction, without impacting on the patient's neurological s...

Applications of artificial intelligence in multimodality cardiovascular imaging: A state-of-the-art review.

Progress in cardiovascular diseases
There has been a tidal wave of recent interest in artificial intelligence (AI), machine learning and deep learning approaches in cardiovascular (CV) medicine. In the era of modern medicine, AI and electronic health records hold the promise to improve...

Deep learning approaches for sleep disorder prediction in an asthma cohort.

The Journal of asthma : official journal of the Association for the Care of Asthma
OBJECTIVE: Sleep is a natural activity of humans that affects physical and mental health; therefore, sleep disturbance may lead to fatigue and lower productivity. This study examined 1 million samples included in the Taiwan National Health Insurance ...

Interpatient Similarities in Cardiac Function: A Platform for Personalized Cardiovascular Medicine.

JACC. Cardiovascular imaging
OBJECTIVES: The authors applied unsupervised machine-learning techniques for integrating echocardiographic features of left ventricular (LV) structure and function into a patient similarity network that predicted major adverse cardiac event(s) (MACE)...

Machine learning and radiomic phenotyping of lower grade gliomas: improving survival prediction.

European radiology
BACKGROUND AND PURPOSE: Recent studies have highlighted the importance of isocitrate dehydrogenase (IDH) mutational status in stratifying biologically distinct subgroups of gliomas. This study aimed to evaluate whether MRI-based radiomic features cou...

Machine Learning in Drug Discovery and Development Part 1: A Primer.

CPT: pharmacometrics & systems pharmacology
Artificial intelligence, in particular machine learning (ML), has emerged as a key promising pillar to overcome the high failure rate in drug development. Here, we present a primer on the ML algorithms most commonly used in drug discovery and develop...