PURPOSE: This study aims to investigate the impact of tumor quadrant location on the 5-year early-stage breast cancer survivability prediction using explainable machine learning (ML) models. By integrating these predictive models with Shapley Additiv...
BACKGROUND: Ovarian cancer (OC), owing to its substantial heterogeneity and high invasiveness, has historically been devoid of precise, individualized treatment options. This study aimed to establish integrated consensus subtypes of OC using differen...
BACKGROUND: Acute pulmonary embolism (APE) is a common and life-threatening emergency in intensive care units (ICUs). Effective risk assessment tools are essential to improve patient outcomes. This study aims to evaluate the association between Simpl...
International journal of surgery (London, England)
Mar 28, 2025
BACKGROUND: The assessment of the International Society of Urological Pathology (ISUP) nuclear grade is crucial for the management and treatment of clear cell renal cell carcinoma (ccRCC). This study aimed to explore the value of using integrated mul...
The most prevalent malignancy among women is breast cancer; hence, treatment approaches are needed in consideration of tumor characteristics and disease stage but also patient preference. Two surgical options, Mastectomy and Breast Conserving Surgery...
This study aimed to develop a machine learning (ML) model for predicting the risk of acute kidney injury (AKI) in diabetic patients with heart failure (HF) during hospitalization. Using data from 1,457 patients in the MIMIC-IV database, the study ide...
Intratumor heterogeneity (ITH) is involved in tumor evolution and drug resistance. Drug sensitivity shows discrepancy in different breast cancer (BRCA) patients due to ITH. The genes mediating ITH in BRCA and their role in predicting prognosis and dr...
BACKGROUND: Chronic pain is a complex condition that affects more than a quarter of people worldwide. The development and progression of chronic pain are unique to each individual due to the contribution of interacting biological, psychological, and ...
Journal of cancer research and clinical oncology
Mar 28, 2025
PURPOSE: To explore the development and validation of automated machine learning (AutoML) models for F-FDG PET imaging-based radiomics signatures to predict treatment response in elderly patients with diffuse large B-cell lymphoma (DLBCL).
BACKGROUND: Liver cancer, particularly hepatocellular carcinoma (HCC), is a major health concern globally and in China, possibly shows recurrence after ablation treatment in high-risk patients. This study investigates the prognosis of early-stage mal...
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