AIMC Topic: Proof of Concept Study
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Computational design of soluble and functional membrane protein analogues.
Nature
Jun 19, 2024
De novo design of complex protein folds using solely computational means remains a substantial challenge. Here we use a robust deep learning pipeline to design complex folds and soluble analogues of integral membrane proteins. Unique membrane topolog...
Prediction of Achilles Tendon Force During Common Motor Tasks From Markerless Video.
IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
Jun 3, 2024
Remodeling of the Achilles tendon (AT) is partly driven by its mechanical environment. AT force can be estimated with neuromusculoskeletal (NMSK) modeling; however, the complex experimental setup required to perform the analyses confines use to the l...
A retrieval-augmented chatbot based on GPT-4 provides appropriate differential diagnosis in gastrointestinal radiology: a proof of concept study.
European radiology experimental
May 17, 2024
BACKGROUND: We investigated the potential of an imaging-aware GPT-4-based chatbot in providing diagnoses based on imaging descriptions of abdominal pathologies.
A multicenter proof-of-concept study on deep learning-based intraoperative discrimination of primary central nervous system lymphoma.
Nature communications
May 4, 2024
Accurate intraoperative differentiation of primary central nervous system lymphoma (PCNSL) remains pivotal in guiding neurosurgical decisions. However, distinguishing PCNSL from other lesions, notably glioma, through frozen sections challenges pathol...
Artificial intelligence and medical education: application in classroom instruction and student assessment using a pharmacology & therapeutics case study.
BMC medical education
Apr 22, 2024
BACKGROUND: Artificial intelligence (AI) tools are designed to create or generate content from their trained parameters using an online conversational interface. AI has opened new avenues in redefining the role boundaries of teachers and learners and...
Prediction of high-risk emergency department revisits from a machine-learning algorithm: a proof-of-concept study.
BMJ health & care informatics
Apr 22, 2024
BACKGROUND: High-risk emergency department (ED) revisit is considered an important quality indicator that may reflect an increase in complications and medical burden. However, because of its multidimensional and highly complex nature, this factor has...
Deep-Learning for Rapid Estimation of the Out-of-Field Dose in External Beam Photon Radiation Therapy - A Proof of Concept.
International journal of radiation oncology, biology, physics
Mar 28, 2024
PURPOSE: The dose deposited outside of the treatment field during external photon beam radiation therapy treatment, also known as out-of-field dose, is the subject of extensive study as it may be associated with a higher risk of developing a second c...
Data extraction for evidence synthesis using a large language model: A proof-of-concept study.
Research synthesis methods
Mar 3, 2024
Data extraction is a crucial, yet labor-intensive and error-prone part of evidence synthesis. To date, efforts to harness machine learning for enhancing efficiency of the data extraction process have fallen short of achieving sufficient accuracy and ...
Deep learning-based prediction of major arrhythmic events in dilated cardiomyopathy: A proof of concept study.
PloS one
Feb 29, 2024
Prediction of major arrhythmic events (MAEs) in dilated cardiomyopathy represents an unmet clinical goal. Computational models and artificial intelligence (AI) are new technological tools that could offer a significant improvement in our ability to p...
Evaluation of an artificial intelligence-facilitated sperm detection tool in azoospermic samples for use in ICSI.
Reproductive biomedicine online
Feb 22, 2024
RESEARCH QUESTION: Can artificial intelligence (AI) improve the efficiency and efficacy of sperm searches in azoospermic samples?
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