AIMC Topic: Prospective Studies

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Diabetic retinopathy as the primary predictor of mild cognitive impairment in type 2 diabetes: Insights from machine learning models.

PloS one
Mild cognitive impairment (MCI) is a significant and increasingly recognized problem in individuals with type 2 diabetes mellitus (T2DM). This study aims to develop a machine-learning model to predict MCI in patients with T2DMThe dataset was obtained...

Autonomous artificial intelligence prescribing a drug to prevent severe acute graft-versus-host disease in HLA-haploidentical transplants.

Nature communications
Autonomous artificial intelligence (AI) models for deciding treatment strategies are available but rarely applied prospectively in clinical settings. Here we present a prospective study of deploying daGOAT, an algorithm we have developed, as a condit...

Single-centre, prospective cohort to predict optimal individualised treatment response in multiple sclerosis (POINT-MS): a cohort profile.

BMJ open
PURPOSE: Multiple sclerosis (MS) is a chronic neurological condition that affects approximately 150 000 people in the UK and presents a significant healthcare burden, including the high costs of disease-modifying treatments (DMTs). DMTs have substant...

Harnessing the Power of Technology to Transform Delirium Severity Measurement in the Intensive Care Unit: Protocol for a Prospective Cohort Study.

JMIR research protocols
BACKGROUND: Delirium, an acute brain dysfunction, is a complication in up to 50% of patients in the intensive care unit (ICU). Measuring and mitigating delirium severity can reduce associated morbidity and improve long-term health outcomes post disch...

Testing the Acceptability and Feasibility of a Gender-Informed Smoking Cessation mHealth App for Women: Mixed Methods Approach.

JMIR human factors
BACKGROUND: Cigarette smoking is a leading cause of preventable morbidity and mortality worldwide. Women who smoke face greater health risks than men, including higher rates of cardiovascular disease and more pronounced declines in lung function. Des...

A machine learning approach to identify patients at risk for long-term consequences after pulmonary embolism.

Scientific reports
Pulmonary embolism (PE) can result in long-term sequelae, such as post-PE syndrome, including persistent dyspnea and chronic thromboembolic pulmonary hypertension (CTEPH). Existing prediction tools for severe post-PE complications lack sensitivity an...

The long-term neuroprotective effect of MIND and Mediterranean diet on patients with Alzheimer's disease.

Scientific reports
Alzheimer's disease is a progressive neurodegenerative disorder with no cure, making preventive strategies crucial. Dietary interventions, particularly the Mediterranean (MeDi) and MIND diets, have been associated with reduced cognitive decline, but ...

Optimized deep learning-accelerated single-breath-hold abdominal HASTE with and without fat saturation improves and accelerates abdominal imaging at 3 Tesla.

BMC medical imaging
BACKGROUND: Deep learning-accelerated single-shot turbo-spin-echo techniques (DL-HASTE) enable single-breath-hold T2-weighted abdominal imaging. However, studies evaluating the image quality of DL-HASTE with and without fat saturation (FS) remain lim...

Predicting Surgical Site Infection after Lumbar Laminectomy and Discectomy: A Cutting-edge Algorithmic Approach by Incorporating Ensembled Stacking into the Current State-of-the-art for Automated Machine Learning.

Neurosurgical review
To develop an algorithmic approach for predicting surgical site infections (SSIs) in patients undergoing lumbar laminectomy and discectomy for adult degenerative spinal disease (DSD) by incorporating ensembled stacking into state-of-the-art (SOTA) au...