AIMC Topic: Pulmonary Disease, Chronic Obstructive

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Integrating bioinformatics and machine learning to unravel shared mechanisms and biomarkers in chronic obstructive pulmonary disease and type 2 diabetes.

Postgraduate medical journal
BACKGROUND: Chronic obstructive pulmonary disease (COPD) and type 2 diabetes mellitus (T2DM) are on the rise. While there is evidence of a link between the two diseases, the pathophysiological mechanisms they share are not fully understood.

Deep Learning-Based Chronic Obstructive Pulmonary Disease Exacerbation Prediction Using Flow-Volume and Volume-Time Curve Imaging: Retrospective Cohort Study.

Journal of medical Internet research
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a common and progressive respiratory condition characterized by persistent airflow limitation and symptoms such as dyspnea, cough, and sputum production. Acute exacerbations (AE) of COPD (AE...

A machine-learning-derived online prediction model for depression risk in COPD patients: A retrospective cohort study from CHARLS.

Journal of affective disorders
BACKGROUND: Depression associated with Chronic Obstructive Pulmonary Disease (COPD) is a detrimental complication that significantly impairs patients' quality of life. This study aims to develop an online predictive model to estimate the risk of depr...

Predictive machine learning algorithm for COPD exacerbations using a digital inhaler with integrated sensors.

BMJ open respiratory research
PURPOSE: By using data obtained with digital inhalers, machine learning models have the potential to detect early signs of deterioration and predict impending exacerbations of chronic obstructive pulmonary disease (COPD) for individual patients. This...

Metabolomic Plasma Profile of Chronic Obstructive Pulmonary Disease Patients.

International journal of molecular sciences
The analysis of blood metabolites may help identify individuals at risk of having COPD and offer insights into its underlying pathophysiology. This study aimed to identify COPD-related metabolic alterations and generate a biological signature potenti...

Identifying GAP43, NMU, and TEX29 as Potential Prognostic Biomarkers for COPD Combined With Lung Cancer Patients Using Machine Learning.

The journal of gene medicine
Chronic obstructive pulmonary disease (COPD) and lung cancer, frequently comorbid conditions intricately linked through smoking, represent significant global health challenges. COPD is a common comorbidity in nonsmall cell lung cancer (NSCLC) patient...

Clinical and Social Characterization of Patients Hospitalized for COPD Exacerbation Using Machine Learning Tools.

Archivos de bronconeumologia
OBJECTIVE: This study aims to employ machine learning (ML) tools to cluster patients hospitalized for acute exacerbations of chronic obstructive pulmonary disease (COPD) based on their diverse social and clinical characteristics. This clustering is i...

[Application of artificial intelligence in combination with CT radiomics in chronic obstructive pulmonary disease].

Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases
As CT imaging is increasingly used for the evaluation of lung nodules and the diagnosis and screening of lung cancer in smokers, we have more opportunities to use CT images to identify patients with early-stage chronic obstructive pulmonary disease(C...

Identifying Common Diagnostic Biomarkers and Therapeutic Targets between COPD and Sepsis: A Bioinformatics and Machine Learning Approach.

International journal of chronic obstructive pulmonary disease
BACKGROUND: Evidence suggests a bidirectional association between chronic obstructive pulmonary disease (COPD) and sepsis, but the underlying mechanisms remain unclear. This study aimed to explore shared diagnostic genes, potential mechanisms, and th...