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Radiotherapy

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High quality proton portal imaging using deep learning for proton radiation therapy: a phantom study.

Biomedical physics & engineering express
Purpose; For shoot-through proton treatments, like FLASH radiotherapy, there will be protons exiting the patient which can be used for proton portal imaging (PPI), revealing valuable information for the validation of tumor location in the beam's-eye-...

External Validation of PATHFx Version 3.0 in Patients Treated Surgically and Nonsurgically for Symptomatic Skeletal Metastases.

Clinical orthopaedics and related research
BACKGROUND: PATHFx is a clinical decision-support tool based on machine learning capable of estimating the likelihood of survival after surgery for patients with skeletal metastases. The applicability of any machine-learning tool depends not only on ...

Artificial Intelligence in radiotherapy: state of the art and future directions.

Medical oncology (Northwood, London, England)
Recent advances in computing capability allowed the development of sophisticated predictive models to assess complex relationships within observational data, described as Artificial Intelligence. Medicine is one of the several fields of application a...

Dosimetry-Driven Quality Measure of Brain Pseudo Computed Tomography Generated From Deep Learning for MRI-Only Radiation Therapy Treatment Planning.

International journal of radiation oncology, biology, physics
PURPOSE: This study aims to evaluate the impact of key parameters on the pseudo computed tomography (pCT) quality generated from magnetic resonance imaging (MRI) with a 3-dimensional (3D) convolutional neural network.

Radiomics and deep learning in lung cancer.

Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]
Lung malignancies have been extensively characterized through radiomics and deep learning. By providing a three-dimensional characterization of the lesion, models based on radiomic features from computed tomography (CT) and positron-emission tomograp...

Machine learning for radiation outcome modeling and prediction.

Medical physics
AIMS: This review paper intends to summarize the application of machine learning to radiotherapy outcome modeling based on structured and un-structured radiation oncology datasets.

System for High-Intensity Evaluation During Radiation Therapy (SHIELD-RT): A Prospective Randomized Study of Machine Learning-Directed Clinical Evaluations During Radiation and Chemoradiation.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology
PURPOSE: Patients undergoing outpatient radiotherapy (RT) or chemoradiation (CRT) frequently require acute care (emergency department evaluation or hospitalization). Machine learning (ML) may guide interventions to reduce this risk. There are limited...

The Application and Development of Deep Learning in Radiotherapy: A Systematic Review.

Technology in cancer research & treatment
With the massive use of computers, the growth and explosion of data has greatly promoted the development of artificial intelligence (AI). The rise of deep learning (DL) algorithms, such as convolutional neural networks (CNN), has provided radiation o...

Prediction of Radiation Pneumonitis With Machine Learning in Stage III Lung Cancer: A Pilot Study.

Technology in cancer research & treatment
BACKGROUND: Radiation pneumonitis (RP) is a dose-limiting toxicity in lung cancer radiotherapy (RT). As risk factors in the development of RP, patient and tumor characteristics, dosimetric parameters, and treatment features are intertwined, and it is...