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Randomized Controlled Trials as Topic

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A 29-gene and cytogenetic score for the prediction of resistance to induction treatment in acute myeloid leukemia.

Haematologica Dec 14, 2017
Primary therapy resistance is a major problem in acute myeloid leukemia treatment. We set out to develop a powerful and robust predictor for therapy resistance for intensively treated adult patients. We used two large gene expression data sets (n=856...
Aged, 80 and over Young Adult Adult Leukemia, Myeloid, Acute Male Machine Learning Prognosis Female Aged Predictive Value of Tests Mutation Remission Induction Survival Analysis Drug Resistance, Neoplasm Middle Aged Gene Expression Profiling Adolescent Randomized Controlled Trials as Topic Humans
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Complications and health-related quality of life after robot-assisted versus open radical cystectomy: a systematic review and meta-analysis of four RCTs.

Systematic reviews Aug 2, 2017
BACKGROUND: Radical cystectomy is associated with high rates of perioperative morbidity. Robotic-assisted radical cystectomy (RARC) is widely used today despite limited evidence for clinical superiority. The aim of this review was to evaluate the eff...
Humans Postoperative Complications Quality of Life Length of Stay Robotics Treatment Outcome Cystectomy Randomized Controlled Trials as Topic
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Robot-Assisted Training for People With Spinal Cord Injury: A Meta-Analysis.

Archives of physical medicine and rehabilitation Jun 20, 2017
OBJECTIVE: To investigate the effects of robot-assisted training on the recovery of people with spinal cord injury (SCI).
Humans Activities of Daily Living Lower Extremity Spinal Cord Injuries Recovery of Function Upper Extremity Randomized Controlled Trials as Topic Physical Therapy Modalities Robotics
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Electromechanical-assisted training for walking after stroke.

The Cochrane database of systematic reviews May 10, 2017
BACKGROUND: Electromechanical- and robotic-assisted gait-training devices are used in rehabilitation and might help to improve walking after stroke. This is an update of a Cochrane Review first published in 2007.
Middle Aged Randomized Controlled Trials as Topic Robotics Equipment Design Humans Aged Walking Speed Orthotic Devices Electric Stimulation Therapy Stroke Rehabilitation Walking Gait Combined Modality Therapy Exercise Therapy
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Is body-weight-supported treadmill training or robotic-assisted gait training superior to overground gait training and other forms of physiotherapy in people with spinal cord injury? A systematic review.

Spinal cord Apr 11, 2017
STUDY DESIGN: Systematic review about randomised trials comparing different training strategies to improve gait in people with spinal cord injuries (SCI).
Physical Therapy Modalities Neurological Rehabilitation Robotics Gait Spinal Cord Injuries Humans Randomized Controlled Trials as Topic
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Effectiveness of endurance exercise training in patients with coronary artery disease: A meta-analysis of randomised controlled trials.

European journal of cardiovascular nursing Dec 19, 2016
BACKGROUND: Exercise interventions apparently reduce the risks of and prevent coronary artery disease (CAD). Developing an exercise intervention for patients with CAD is a rapidly expanding focus worldwide. The results of previous studies are inconsi...
Coronary Artery Disease Humans Adult Exercise Therapy Female Male Aged Middle Aged Aged, 80 and over Randomized Controlled Trials as Topic
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A systematic review and meta-analysis of the effect of prophylactic tranexamic acid treatment in major benign uterine surgery.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics Dec 9, 2016
BACKGROUND: The value of tranexamic acid (TA) treatment as bleeding prophylaxis in major uterine surgery is unclear.
Tranexamic Acid Antifibrinolytic Agents Gynecologic Surgical Procedures Cesarean Section Humans Blood Loss, Surgical Pregnancy Blood Transfusion Female Randomized Controlled Trials as Topic
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Efficacy according to blind independent central review: Post-hoc analyses from the phase III, randomized, multicenter, IPASS study of first-line gefitinib versus carboplatin/paclitaxel in Asian patients with EGFR mutation-positive advanced NSCLC.

Lung cancer (Amsterdam, Netherlands) Nov 30, 2016
OBJECTIVE: The Phase III, randomized, open-label IPASS study (NCT00322452) of first-line epidermal growth factor receptor tyrosine kinase inhibitor (EGFR TKI) gefitinib versus carboplatin/paclitaxel for Asian patients with advanced non-small-cell lun...
Mutation Asian People Carboplatin Paclitaxel ErbB Receptors Protein Kinase Inhibitors Gefitinib Humans Disease-Free Survival Female Smoking Adenocarcinoma Aged Quinazolines Carcinoma, Non-Small-Cell Lung Aged, 80 and over Middle Aged Randomized Controlled Trials as Topic Male Antineoplastic Agents Neoplasm Staging Lung Neoplasms Antineoplastic Combined Chemotherapy Protocols
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Patient-level meta-analysis of efficacy and hypoglycaemia in people with type 2 diabetes initiating insulin glargine 100U/mL or neutral protamine Hagedorn insulin analysed according to concomitant oral antidiabetes therapy.

Diabetes research and clinical practice Nov 9, 2016
AIMS: Evaluate efficacy and hypoglycaemia according to concomitant oral antidiabetes drug (OAD) in people with type 2 diabetes initiating insulin glargine 100U/mL (Gla-100) or neutral protamine Hagedorn (NPH) insulin once daily.
Clinical Trials, Phase III as Topic Clinical Trials, Phase IV as Topic Insulin, Isophane Sulfonylurea Compounds Hypoglycemia Administration, Oral Drug Therapy, Combination Weight Gain Treatment Outcome Randomized Controlled Trials as Topic Humans Glycated Hemoglobin Incidence Insulin Glargine Diabetes Mellitus, Type 2 Female Hypoglycemic Agents Male
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Analysis of Machine Learning Techniques for Heart Failure Readmissions.

Circulation. Cardiovascular quality and outcomes Nov 8, 2016
BACKGROUND: The current ability to predict readmissions in patients with heart failure is modest at best. It is unclear whether machine learning techniques that address higher dimensional, nonlinear relationships among variables would enhance predict...
Logistic Models Support Vector Machine Randomized Controlled Trials as Topic Heart Failure Male Middle Aged Risk Assessment Time Factors Data Mining Telemedicine Patient Readmission Nonlinear Dynamics Humans Reproducibility of Results Databases, Factual Algorithms Risk Factors Female Aged
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