BACKGROUND: With nearly one-third of patients with advanced non-small cell lung cancer (NSCLC) and PD-L1 Tumor Proportion Score≥50% surviving beyond 5 years following first-line pembrolizumab, long-term outcomes challenge traditional paradigms of can...
To investigate the impact of retinal fluid dynamics on visual outcomes in patients with treatment-naïve neovascular age-related macular degeneration (nAMD) treated in the real world over 5 years using approved AI-based fluid monitoring. Real-world da...
Pulmonary embolism (PE) can result in long-term sequelae, such as post-PE syndrome, including persistent dyspnea and chronic thromboembolic pulmonary hypertension (CTEPH). Existing prediction tools for severe post-PE complications lack sensitivity an...
BACKGROUND: Antipsychotic medications are frequently prescribed to older residents of long-term care facilities (LTCFs) despite their limited efficacy and considerable safety risks. While discontinuation of these drugs might help reduce their associa...
The American journal of sports medicine
Aug 15, 2025
BACKGROUND: Treatment decisions in patients with anterior cruciate ligament (ACL) injuries are influenced by multiple factors, such as the desire to return to sports or symptomatic instability. Identifying the differential treatment effect of ACL rec...
BACKGROUND: Traumatic brain injury (TBI) is among the most prevalent causes of emergency department visits globally. TBI leads to high morbidity and mortality rates, which poses a noteworthy burden on the medical system regarding both patients and ec...
BACKGROUND: Racially minoritized populations in the United States (US), notably African American (AA) and American Indian/Alaska Native (AI/AN), experience disproportionately higher rates of chronic kidney disease (CKD), diabetes, and hypertension co...
Patient identification for national registries often relies upon clinician recognition of cases or retrospective searches using potentially inaccurate clinical codes, leading to incomplete data capture and inefficiencies. Natural Language Processing ...
BACKGROUND: Standardized registries, such as the International Classification of Diseases (ICD) codes, are commonly built using administrative codes assigned to patient encounters. However, patients with fall injury are often coded using subsequent i...
Neonatal mortality poses a critical challenge in global health, particularly in low- and middle-income countries. Leveraging advancements in technology, such as machine learning (ML) algorithms, offers the potential to improve neonatal care by enabli...
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