AIMC Topic: Sensitivity and Specificity

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Protocol for the diagnosis of keratoconus using convolutional neural networks.

PloS one
Keratoconus is the corneal disease with the highest reported incidence of 1:2000. The treatment's level of success highly depends on how early it was started. Subsequently, a fast and highly capable diagnostic tool is crucial. While there are many co...

Deep learning-based diagnosis models for onychomycosis in dermoscopy.

Mycoses
BACKGROUND: Onychomycosis is a common disease. Emerging noninvasive, real-time techniques such as dermoscopy and deep convolutional neural networks have been proposed for the diagnosis of onychomycosis. However, deep learning application in dermoscop...

Efficient SARS-CoV-2 Quantitative Reverse Transcriptase PCR Saliva Diagnostic Strategy utilizing Open-Source Pipetting Robots.

Journal of visualized experiments : JoVE
The emergence of the recent SARS-CoV-2 global health crisis introduced key challenges for epidemiological research and clinical testing. Characterized by a high rate of transmission and low mortality, the COVID-19 pandemic necessitated accurate and e...

A non-invasive method for concurrent detection of early-stage women-specific cancers.

Scientific reports
We integrated untargeted serum metabolomics using high-resolution mass spectrometry with data analysis using machine learning algorithms to accurately detect early stages of the women specific cancers of breast, endometrium, cervix, and ovary across ...

Detecting obstructive sleep apnea by craniofacial image-based deep learning.

Sleep & breathing = Schlaf & Atmung
STUDY OBJECTIVES: This study aimed to develop a deep learning-based model to detect obstructive sleep apnea (OSA) using craniofacial photographs.

Identification of parameters and formulation of a statistical and machine learning model to identify Babesia canis infections in dogs using available ADVIA hematology analyzer data.

Parasites & vectors
BACKGROUND: Canine babesiosis is an important tick-borne disease in endemic regions. One of the relevant subspecies in Europe is Babesia canis, and it can cause severe clinical signs such as hemolytic anemia. Apart from acute clinical symptoms dogs c...

A multiple testing framework for diagnostic accuracy studies with co-primary endpoints.

Statistics in medicine
Major advances have been made regarding the utilization of machine learning techniques for disease diagnosis and prognosis based on complex and high-dimensional data. Despite all justified enthusiasm, overoptimistic assessments of predictive performa...

The application of a deep learning system developed to reduce the time for RT-PCR in COVID-19 detection.

Scientific reports
Reducing the time to diagnose COVID-19 helps to manage insufficient isolation-bed resources and adequately accommodate critically ill patients. There is currently no alternative method to real-time reverse transcriptase polymerase chain reaction (RT-...