AIMC Topic: Sex Factors

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Serum Cardiac Troponin T Levels in Asymptomatic Elderly Nursing Home Residents.

The American journal of medicine
BACKGROUND: The definition of myocardial infarction relies on elevated troponin levels. However, elevated levels of high sensitive cardiac troponin (hs-cTnT) assays have been reported in elderly patients without acute myocardial infarction. We sought...

Differential effects of childhood neglect and abuse during sensitive exposure periods on male and female hippocampus.

NeuroImage
The hippocampus is a highly stress susceptible structure and hippocampal abnormalities have been reported in a host of psychiatric disorders including major depression and post-traumatic stress disorder (PTSD). The hippocampus appears to be particula...

Broad clinical spectrum and diverse outcomes of prolactinoma with pediatric onset: medication-resistant and recurrent cases.

Endocrine journal
Prolactinoma is a benign tumor of the pituitary gland that rarely occurs in children and adolescents; thus, the clinical spectrum and long-term prognosis in these patients remain unknown. This study was performed to investigate the long-term outcomes...

Mechanisms of pulse pressure amplification dipping pattern during sleep time: the SAFAR study.

Journal of the American Society of Hypertension : JASH
The difference in pulse pressure (PP) between peripheral arteries and the aorta, called pulse pressure amplification (PPamp), is a well-described physiological phenomenon independently associated with cardiovascular events. Recent studies suggest tha...

Estimating causal effects for survival (time-to-event) outcomes by combining classification tree analysis and propensity score weighting.

Journal of evaluation in clinical practice
RATIONALE, AIMS AND OBJECTIVES: A common approach to assessing treatment effects in nonrandomized studies with time-to-event outcomes is to estimate propensity scores and compute weights using logistic regression, test for covariate balance, and then...

Identifying causal mechanisms in health care interventions using classification tree analysis.

Journal of evaluation in clinical practice
RATIONALE, AIMS, AND OBJECTIVES: Mediation analysis identifies causal pathways by testing the relationships between the treatment, the outcome, and an intermediate variable that mediates the relationship between the treatment and outcome. This paper ...

Poor vitamin D status increases the risk of anemia in school children: National Food and Nutrition Surveillance.

Nutrition (Burbank, Los Angeles County, Calif.)
OBJECTIVES: This study aimed to investigate the association between 25-hydroxyvitamin D (25[OH]D) concentrations and the risk of anemia in a large cohort of children with consideration for the effects of sex, body mass index (BMI), serum intact parat...

Using artificial neural networks to select the parameters for the prognostic of mild cognitive impairment and dementia in elderly individuals.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVES: A huge number of solutions based on computational systems have been recently developed for the classification of cognitive abnormalities in older people, so that individuals at high risk of developing neurodegenerative dise...

Modeling time-to-event (survival) data using classification tree analysis.

Journal of evaluation in clinical practice
RATIONALE, AIMS, AND OBJECTIVES: Time to the occurrence of an event is often studied in health research. Survival analysis differs from other designs in that follow-up times for individuals who do not experience the event by the end of the study (cal...