AIMC Topic: Software

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Installing a Local Copy of the Reactome Web Site and Knowledgebase.

Current protocols in bioinformatics Jun 19, 2015
The Reactome project builds, maintains, and publishes a knowledgebase of biological pathways. The information in the knowledgebase is gathered from the experts in the field, peer reviewed and edited by Reactome editorial staff, and then published to ...
Databases as Topic Software Signal Transduction Internet Knowledge Bases
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Better prediction of functional effects for sequence variants.

BMC genomics Jun 18, 2015
Elucidating the effects of naturally occurring genetic variation is one of the major challenges for personalized health and personalized medicine. Here, we introduce SNAP2, a novel neural network based classifier that improves over the state-of-the-a...
Computational Biology Evolution, Molecular Genetic Variation Protein Isoforms Humans Neural Networks, Computer Software
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TPpred3 detects and discriminates mitochondrial and chloroplastic targeting peptides in eukaryotic proteins.

Bioinformatics (Oxford, England) Jun 16, 2015
MOTIVATION: Molecular recognition of N-terminal targeting peptides is the most common mechanism controlling the import of nuclear-encoded proteins into mitochondria and chloroplasts. When experimental information is lacking, computational methods can...
Machine Learning Software Peptides Support Vector Machine Mitochondria Protein Transport Eukaryota Chloroplasts Sequence Analysis, Protein Mitochondrial Proteins Chloroplast Proteins
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TENET: topological feature-based target characterization in signalling networks.

Bioinformatics (Oxford, England) Jun 16, 2015
MOTIVATION: Target characterization for a biochemical network is a heuristic evaluation process that produces a characterization model that may aid in predicting the suitability of each molecule for drug targeting. These approaches are typically used...
Signal Transduction Humans Support Vector Machine Software Protein Interaction Mapping Algorithms
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FoodWiki: Ontology-Driven Mobile Safe Food Consumption System.

TheScientificWorldJournal Jun 15, 2015
An ontology-driven safe food consumption mobile system is considered. Over 3,000 compounds are being added to processed food, with numerous effects on the food: to add color, stabilize, texturize, preserve, sweeten, thicken, add flavor, soften, emuls...
Programming Languages Semantics Food Additives Feeding Behavior Food Motor Activity Basal Metabolism Body Mass Index Blood Pressure Internet Knowledge Bases Software Algorithms Models, Theoretical
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Using natural language processing to provide personalized learning opportunities from trainee clinical notes.

Journal of biomedical informatics Jun 10, 2015
OBJECTIVE: Assessment of medical trainee learning through pre-defined competencies is now commonplace in schools of medicine. We describe a novel electronic advisor system using natural language processing (NLP) to identify two geriatric medicine com...
Tennessee Advance Directives Clinical Clerkship User-Computer Interface Educational Measurement Natural Language Processing Outcome Assessment, Health Care Academic Medical Centers Education, Medical Automation Hospitals, Veterans Aged Students, Medical Middle Aged Clinical Competence Geriatrics Learning Humans Reproducibility of Results Software Algorithms Mental Disorders Electronic Health Records
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Understanding safety-critical interactions with a home medical device through Distributed Cognition.

Journal of biomedical informatics Jun 6, 2015
As healthcare shifts from the hospital to the home, it is becoming increasingly important to understand how patients interact with home medical devices, to inform the safe and patient-friendly design of these devices. Distributed Cognition (DCog) has...
Humans Artificial Intelligence Software Algorithms Male Middle Aged Renal Dialysis Residence Characteristics Patient Safety Female Aged Adult Anthropology, Cultural Artifacts Hemodialysis, Home United Kingdom Renal Insufficiency Interior Design and Furnishings Decision Making Data Collection Equipment and Supplies
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Summarizing and visualizing structural changes during the evolution of biomedical ontologies using a Diff Abstraction Network.

Journal of biomedical informatics Jun 3, 2015
Biomedical ontologies are a critical component in biomedical research and practice. As an ontology evolves, its structure and content change in response to additions, deletions and updates. When editing a biomedical ontology, small local updates may ...
Vocabulary, Controlled Data Collection Sleep Biological Ontologies Software Algorithms Technology Biomedical Research Drug Design Quality Control
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Visualization and Interpretation of Support Vector Machine Activity Predictions.

Journal of chemical information and modeling Jun 2, 2015
Support vector machines (SVMs) are among the preferred machine learning algorithms for virtual compound screening and activity prediction because of their frequently observed high performance levels. However, a well-known conundrum of SVMs (and other...
Humans Software Algorithms Protein Kinase Inhibitors Receptors, Dopamine D2 Mitogen-Activated Protein Kinase 14 Receptor, Cannabinoid, CB2 Support Vector Machine Drug Evaluation, Preclinical Ligands Linear Models
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Practical Recommendations for Robot-Assisted Treadmill Therapy (Lokomat) in Children with Cerebral Palsy: Indications, Goal Setting, and Clinical Implementation within the WHO-ICF Framework.

Neuropediatrics May 26, 2015
Active participation and the highest level of independence during daily living are primary goals in neurorehabilitation. Therefore, standing and walking are key factors in many rehabilitation programs. Despite inconclusive evidence considering the be...
Exercise Therapy Goals Cerebral Palsy Child Treatment Outcome Humans Robotics Software Walking User-Computer Interface Child, Preschool
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