AIMC Topic: Transforming Growth Factor beta

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Lipidome-based rapid diagnosis with machine learning for detection of TGF-β signalling activated area in head and neck cancer.

British journal of cancer
BACKGROUND: Several pro-oncogenic signals, including transforming growth factor beta (TGF-β) signalling from tumour microenvironment, generate intratumoural phenotypic heterogeneity and result in tumour progression and treatment failure. However, the...

Study on miR-384-5p activates TGF-β signaling pathway to promote neuronal damage in abutment nucleus of rats based on deep learning.

Artificial intelligence in medicine
BACKGROUND: Any ailment in our organs can be visualized by using different modality signals and images. Hospitals are encountering a massive influx of large multimodality patient data to be analysed accurately and with context understanding. The deep...

The effects of a therapeutic formalin bath on selected immunological and oxidative stress parameters in common carp (Cyprinus carpio).

The Science of the total environment
Formalin is commonly used as a component of antiparasitic baths in fisheries. In this study the impact of this bath on the immune profile and oxidative stress parameters was evaluated. A formalin bath was prepared in the concentration of 185.3 mg L (...

[Advances in mechanotransduction signaling pathways in distraction osteogenesis].

Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery
OBJECTIVE: To review the role and research progress of mechanotransduction signaling pathway in distraction osteogenesis, so as to provide theoretical basis and reference for clinical treatment.

6-Gingerol inhibits hair cycle via induction of MMP2 and MMP9 expression.

Anais da Academia Brasileira de Ciencias
6-Gingerol is the major active constituent of ginger. In the current study, we aimed to investigate the mechanisms underlying the effects of 6-Gingerol on hair growth. Mice were randomly divided into five groups; after hair depilation (day 0), mice w...

Osteoinductive Activity of DFDBA Materials versus Growth Factors on Gene Expression of MG-63 Cells: An In Vitro Study.

Journal of long-term effects of medical implants
Guided bone regeneration using demineralized freeze-dried bone allograft (DFDBA) and growth factors (GFs) is a current goal in implant dentistry because of their potential osteoinductive abilities. Regarding controversial results, the purpose of this...

Effects of TGF-β1 on the Proliferation and Apoptosis of Human Cervical Cancer Hela Cells In Vitro.

Cell biochemistry and biophysics
To investigate the effects of TGF-β1 on the proliferation and apoptosis of cervical cancer Hela cells in vitro. Human cervical cancer Hela cells were cultured in vitro and divided into the experimental and control groups. In the experimental groups, ...