AIMC Topic: Treatment Failure

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Robot-assisted Laparoscopic Bilateral Ileal Ureter in Duplex Ureter With Strictures After Treatment Failure of Allium Stents.

Urology Aug 21, 2022
BACKGROUND: Ureteral injury and vaginal fistula are common complications after surgical treatment and radiotherapy of gynecological tumor. Ureteral injury in duplex system is more challenging and rarely reported. OBJECTIVE: We report our surgical tec...
Humans Female Middle Aged Allium Robotics Treatment Failure Laparoscopy Ureter Robotic Surgical Procedures Ureteral Obstruction Constriction, Pathologic Vaginal Fistula Stents
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Risk prediction of clinical adverse outcomes with machine learning in a cohort of critically ill patients with atrial fibrillation.

Scientific reports Sep 23, 2021
Critically ill patients affected by atrial fibrillation are at high risk of adverse events: however, the actual risk stratification models for haemorrhagic and thrombotic events are not validated in a critical care setting. With this paper we aimed t...
Treatment Failure Ischemic Attack, Transient Hospital Mortality Stroke Atrial Fibrillation Hemorrhage Machine Learning Retrospective Studies Critical Illness Intensive Care Units Female Risk Factors Aged Aged, 80 and over Male Risk Assessment Humans
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CKLF and IL1B transcript levels at diagnosis are predictive of relapse in children with pre-B-cell acute lymphoblastic leukaemia.

British journal of haematology Feb 23, 2021
Disease relapse is the greatest cause of treatment failure in paediatric B-cell acute lymphoblastic leukaemia (B-ALL). Current risk stratifications fail to capture all patients at risk of relapse. Herein, we used a machine-learning approach to identi...
Humans Transcriptome Adolescent Child, Preschool Child Predictive Value of Tests Machine Learning Female Male Risk Assessment Infant Chemokines Recurrence Precursor B-Cell Lymphoblastic Leukemia-Lymphoma MARVEL Domain-Containing Proteins Interleukin-1beta Acute Disease Survival Analysis Treatment Failure
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A machine learning-based framework for Predicting Treatment Failure in tuberculosis: A case study of six countries.

Tuberculosis (Edinburgh, Scotland) Jun 23, 2020
Tuberculosis is ranked as the 2nd deadliest disease in the world and is responsible for ten million deaths in 2017. Treatment failure is one of a main reason behind these deaths. Reasons of treatment failure are still unknown and the death rate due t...
Antitubercular Agents Tuberculosis Mycobacterium tuberculosis Treatment Failure Risk Factors Risk Assessment Support Vector Machine Predictive Value of Tests Humans Neural Networks, Computer Machine Learning Decision Support Techniques Reproducibility of Results
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Development of a machine learning algorithm for prediction of failure of nonoperative management in spinal epidural abscess.

The spine journal : official journal of the North American Spine Society May 4, 2019
BACKGROUND CONTEXT: Data regarding risk of failure of nonoperative management in spinal epidural abscess (SEA) are limited. Given the potential for deterioration with treatment failure, a tool that predicts the probability of failure would be of grea...
Logistic Models Treatment Failure Spinal Diseases Epidural Abscess Female Risk Factors Adult Male Middle Aged Humans Machine Learning Anti-Bacterial Agents
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Defining and discriminating responders from non-responders following transurethral resection of the prostate.

Scandinavian journal of urology Jan 25, 2019
BACKGROUND: Transurethral resection of the prostate (TURP) is the reference standard surgical treatment for lower urinary tract symptoms (LUTS) related to benign prostatic enlargement. The aim of this study was to investigate the response rate follow...
Male Middle Aged Length of Stay Logistic Models Urinary Catheterization Treatment Outcome Urinary Retention Humans Prostatic Hyperplasia Aged Transurethral Resection of Prostate Multivariate Analysis Treatment Failure Lower Urinary Tract Symptoms
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Predictors of Nodal and Metastatic Failure in Early Stage Non-small-cell Lung Cancer After Stereotactic Body Radiation Therapy.

Clinical lung cancer Dec 29, 2018
INTRODUCTION/BACKGROUND: Many patients with early stage non-small-cell lung cancer (ES-NSCLC) undergoing stereotactic body radiation therapy (SBRT) develop metastases, which is associated with poor outcomes. We sought to identify factors predictive o...
Radiosurgery Middle Aged Treatment Failure Risk Factors Aged Follow-Up Studies Disease Progression Humans Aged, 80 and over Lymphatic Metastasis Lung Neoplasms Prognosis Adult Neoplasm Staging Carcinoma, Non-Small-Cell Lung Retrospective Studies Male Tumor Burden Female Radiotherapy Dosage
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Development of deep neural network for individualized hepatobiliary toxicity prediction after liver SBRT.

Medical physics Sep 10, 2018
BACKGROUND: Accurate prediction of radiation toxicity of healthy organs-at-risks (OARs) critically determines the radiation therapy (RT) success. The existing dose-volume histogram-based metric may grossly under/overestimate the therapeutic toxicity ...
Biliary Tract Humans Neural Networks, Computer Precision Medicine Liver Organs at Risk Radiotherapy Planning, Computer-Assisted Radiotherapy Dosage Radiosurgery Treatment Failure Risk
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Salvage HDR Brachytherapy: Multiple Hypothesis Testing Versus Machine Learning Analysis.

International journal of radiation oncology, biology, physics Mar 13, 2018
PURPOSE: Salvage high-dose-rate brachytherapy (sHDRB) is a treatment option for recurrences after prior radiation therapy. However, only approximately 50% of patients benefit, with the majority of second recurrences after salvage brachytherapy occurr...
Humans Linear Models Salvage Therapy Brachytherapy Machine Learning Treatment Failure Retrospective Studies Recurrence Male Prostatic Neoplasms
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Efficacy and safety of lebrikizumab in adult patients with mild-to-moderate asthma not receiving inhaled corticosteroids.

Respiratory medicine Dec 13, 2017
BACKGROUND: Asthma is a heterogeneous and complex disease in both its clinical course and response to treatment. IL-13 is central to Type 2 inflammation and contributes to many features of asthma. In a previous Phase 2 study, lebrikizumab, an anti-IL...
Double-Blind Method Forced Expiratory Volume Acetates Sulfides Treatment Failure Quinolines Administration, Inhalation Anti-Asthmatic Agents Severity of Illness Index Humans Injections, Subcutaneous Female Treatment Outcome Adult Cyclopropanes Antibodies, Monoclonal Asthma Male Middle Aged Glucocorticoids
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