AIMC Topic: Treatment Outcome

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Inductive reasoning with large language models: A simulated randomized controlled trial for epilepsy.

Epilepsy research
INTRODUCTION: To investigate the potential of using artificial intelligence (AI), specifically large language models (LLMs), for synthesizing information in a simulated randomized clinical trial (RCT) for an anti-seizure medication, cenobamate, demon...

[MP-MRI in the evaluation of non-operative treatment response, for residual and recurrent tumor detection in head and neck cancer].

Magyar onkologia
As non-surgical therapies gain acceptance in head and neck tumors, the importance of imaging has increased. New therapeutic methods (in radiation therapy, targeted biological therapy, immunotherapy) need better tumor characterization and prognostic i...

Application of causal forests to randomised controlled trial data to identify heterogeneous treatment effects: a case study.

BMC medical research methodology
BACKGROUND: Classical approaches to subgroup analysis in randomised controlled trials (RCTs) to identify heterogeneous treatment effects (HTEs) involve testing the interaction between each pre-specified possible treatment effect modifier and the trea...

Machine Learning in Intravascular Ultrasound: Validating Automated Lesion Assessment for Complex Coronary Interventions.

Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions
BACKGROUND: Intravascular ultrasound (IVUS) is essential for assessing complex coronary lesions, but remains underutilized in part due to difficulties in image interpretation. The AVVIGO IVUS Automated Lesion Assessment (ALA) software, which uses mac...

An Integrative Machine Learning Model for Predicting Early Safety Outcomes in Patients Undergoing Transcatheter Aortic Valve Implantation.

Medicina (Kaunas, Lithuania)
: Early safety outcomes following transcatheter aortic valve implantation (TAVI) for severe aortic stenosis are critical for patient prognosis. Accurate prediction of adverse events can enhance patient management and improve outcomes. : This study ai...

Plasma Cytokine and Chemokine Profiles Predict Efficacy and Toxicity of Anti-CD19 CAR-T Cell Therapy in Large B-Cell Lymphoma.

Clinical lymphoma, myeloma & leukemia
BACKGROUND: Anti-CD19 chimeric antigen receptor T-cell (CAR-T) therapy has emerged as a promising treatment for large B-cell lymphoma (LBCL); however, durable complete responses are achieved in only 30% to 40% of patients. Additionally, CAR-T therapy...

Robotic beds for the treatment of positional obstructive sleep apnea - A randomized cross-over pilot trial.

Sleep medicine
BACKGROUND: Interventions leading to avoidance of supine position and thus reducing the likelihood of upper airway collapse during sleep are a treatment approach for positional obstructive sleep apnea (POSA). The aim of this randomized cross-over tri...

Predicting Treatment Response of Repetitive Transcranial Magnetic Stimulation in Major Depressive Disorder Using an Explainable Machine Learning Model Based on Electroencephalography and Clinical Features.

Biological psychiatry. Cognitive neuroscience and neuroimaging
Major depressive disorder (MDD) is highly heterogeneous in response to repetitive transcranial magnetic stimulation (rTMS), and identifying predictive biomarkers is essential for personalized treatment. However, most prior research studies have used ...

Clinical efficacy of NIBS in enhancing neuroplasticity for stroke recovery.

Journal of neuroscience methods
BACKGROUND: For stroke patients, a therapeutic approach named Non-invasive brain stimulation (NIBS) was applied and it has gained attention. This NIBS approach enhances the neuroplasticity and facilitates in functional Stroke Rehabilitation (SR) thro...