INTRODUCTION: To investigate the potential of using artificial intelligence (AI), specifically large language models (LLMs), for synthesizing information in a simulated randomized clinical trial (RCT) for an anti-seizure medication, cenobamate, demon...
As non-surgical therapies gain acceptance in head and neck tumors, the importance of imaging has increased. New therapeutic methods (in radiation therapy, targeted biological therapy, immunotherapy) need better tumor characterization and prognostic i...
BACKGROUND: Classical approaches to subgroup analysis in randomised controlled trials (RCTs) to identify heterogeneous treatment effects (HTEs) involve testing the interaction between each pre-specified possible treatment effect modifier and the trea...
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions
Feb 21, 2025
BACKGROUND: Intravascular ultrasound (IVUS) is essential for assessing complex coronary lesions, but remains underutilized in part due to difficulties in image interpretation. The AVVIGO IVUS Automated Lesion Assessment (ALA) software, which uses mac...
: Early safety outcomes following transcatheter aortic valve implantation (TAVI) for severe aortic stenosis are critical for patient prognosis. Accurate prediction of adverse events can enhance patient management and improve outcomes. : This study ai...
Clinical lymphoma, myeloma & leukemia
Feb 20, 2025
BACKGROUND: Anti-CD19 chimeric antigen receptor T-cell (CAR-T) therapy has emerged as a promising treatment for large B-cell lymphoma (LBCL); however, durable complete responses are achieved in only 30% to 40% of patients. Additionally, CAR-T therapy...
BACKGROUND: Interventions leading to avoidance of supine position and thus reducing the likelihood of upper airway collapse during sleep are a treatment approach for positional obstructive sleep apnea (POSA). The aim of this randomized cross-over tri...
PURPOSE: To utilize a convolutional neural network (CNN) to predict the response of treatment-naïve diabetic macular edema (DME) to a single injection of anti-vascular endothelial growth factor (anti-VEGF) with data from optical coherence tomography ...
Biological psychiatry. Cognitive neuroscience and neuroimaging
Feb 18, 2025
Major depressive disorder (MDD) is highly heterogeneous in response to repetitive transcranial magnetic stimulation (rTMS), and identifying predictive biomarkers is essential for personalized treatment. However, most prior research studies have used ...
BACKGROUND: For stroke patients, a therapeutic approach named Non-invasive brain stimulation (NIBS) was applied and it has gained attention. This NIBS approach enhances the neuroplasticity and facilitates in functional Stroke Rehabilitation (SR) thro...
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