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Treatment Outcome

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Multimodal deep learning for predicting PD-L1 biomarker and clinical immunotherapy outcomes of esophageal cancer.

Frontiers in immunology
Although the immune checkpoint inhibitors (ICIs) have demonstrated remarkable anti-tumor efficacy in solid tumors, the proportion of ESCC patients who benefit from ICIs remains limited. Current biomarkers have assisted in identifying potential respon...

An Integrative Machine Learning Model for Predicting Early Safety Outcomes in Patients Undergoing Transcatheter Aortic Valve Implantation.

Medicina (Kaunas, Lithuania)
: Early safety outcomes following transcatheter aortic valve implantation (TAVI) for severe aortic stenosis are critical for patient prognosis. Accurate prediction of adverse events can enhance patient management and improve outcomes. : This study ai...

Identifying responders to gabapentin for the treatment of alcohol use disorder: an exploratory machine learning approach.

Alcohol and alcoholism (Oxford, Oxfordshire)
BACKGROUND: Gabapentin, an anticonvulsant medication, has been proposed as a treatment for alcohol use disorder (AUD). A multisite study tested gabapentin enacarbil extended-release (GE-XR; 600 mg/twice a day), a prodrug formulation, combined with a ...

Prediction of Chemotherapy Response in Locally Advanced Breast Cancer Patients at Pre-Treatment Using CT Textural Features and Machine Learning: Comparison of Feature Selection Methods.

Tomography (Ann Arbor, Mich.)
RATIONALE: Neoadjuvant chemotherapy (NAC) is a key element of treatment for locally advanced breast cancer (LABC). Predicting the response of NAC for patients with LABC before initiating treatment would be valuable to customize therapies and ensure t...

Predicting Therapy Outcomes in Patients With Stress-Related Disorders: Protocol for a Predictive Modeling Study.

JMIR research protocols
BACKGROUND: While cognitive behavioral therapy has shown efficacy in treating stress-related disorders, such as adjustment disorder and exhaustion disorder, knowledge about factors contributing to treatment response is limited. Improved identificatio...

Preoperative prediction of textbook outcome in intrahepatic cholangiocarcinoma by interpretable machine learning: A multicenter cohort study.

World journal of gastroenterology
BACKGROUND: To investigate the preoperative factors influencing textbook outcomes (TO) in Intrahepatic cholangiocarcinoma (ICC) patients and evaluate the feasibility of an interpretable machine learning model for preoperative prediction of TO, we dev...

Application of machine learning models to identify predictors of good outcome after laparoscopic fundoplication.

Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract
BACKGROUND: Laparoscopic fundoplication remains the gold standard treatment for gastroesophageal reflux disease. However, 10% to 20% of patients experience new, persistent, or recurrent symptoms warranting further treatment. Potential predictors for ...

Machine learning models for prediction of NPVR ≥80% with HIFU ablation for uterine fibroids.

International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group
BACKGROUND: Currently high-intensity focused ultrasound (HIFU) is widely used to treat uterine fibroids (UFs). The aim of this study is to develop a machine learning model that can accurately predict the efficacy of HIFU ablation for UFs, assisting t...

Machine learning-based prediction of vesicoureteral reflux outcomes in infants under antibiotic prophylaxis.

Scientific reports
We aimed to investigate the independent outcome predictors of continuous antibiotic prophylaxis (CAP) in vesicoureteral reflux, train a model to predict the outcome, and evaluate which infants should be referred for endoscopic vesicoureteral reflux c...