AIMC Topic: Tumor Necrosis Factor-alpha

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[Qinghuachang Decoction Inhibited NF-kappaB Activation in LPS-induced Human Enterocytes].

Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine Nov 1, 2015
OBJECTIVE: To explore anti-inflammation and mechanism of Qinghuachang Decoction (QD) by using LPS stimulated differentiated colon cancer Caco-2 cells (as an inflammation model of human enterocytes).
Humans Tumor Necrosis Factor-alpha Colon Inflammation Lipopolysaccharides Caco-2 Cells Phosphorylation Interleukin-8 Drugs, Chinese Herbal NF-kappa B NF-KappaB Inhibitor alpha Enterocytes I-kappa B Proteins
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[Reproduction of a model of "two-hit" sepsis model with complication of pneumonia in rat].

Zhonghua wei zhong bing ji jiu yi xue Oct 1, 2015
OBJECTIVE: To reproduce a clinically relevant "two-hit" model of sepsis complicated by pneumonia and to explore the correlation between "two-hit" and immune state.
Tumor Necrosis Factor-alpha Interleukin-6 Animals Male Sepsis Rats Rats, Sprague-Dawley Disease Models, Animal Apoptosis Pneumonia HMGB1 Protein Interleukin-1beta Transforming Growth Factor beta1 Creatinine Alanine Transaminase Aspartate Aminotransferases Random Allocation Spleen Blood Urea Nitrogen Receptors, Tumor Necrosis Factor, Type I
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