AIMC Topic: X-Ray Diffraction

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Improving Dissolution Rate of Carbamazepine-Glutaric Acid Cocrystal Through Solubilization by Excess Coformer.

Pharmaceutical research Dec 29, 2017
PURPOSE: The use of soluble cocrystals is a promising strategy for delivering poorly soluble drugs. However, precipitation of poorly soluble crystal form during dissolution hinders the successful tablet development of cocrystals. This work was aimed ...
Crystallization Viscosity X-Ray Diffraction Chemistry, Pharmaceutical Carbamazepine Glutarates Kinetics Humans Tablets Water Solubility Powders Drug Stability
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Amine-Functionalized Sugarcane Bagasse: A Renewable Catalyst for Efficient Continuous Flow Knoevenagel Condensation Reaction at Room Temperature.

Molecules (Basel, Switzerland) Dec 24, 2017
A biomass-based catalyst with amine groups (-NH₂), viz., amine-functionalized sugarcane bagasse (SCB-NH₂), was prepared through the amination of sugarcane bagasse (SCB) in a two-step process. The physicochemical properties of the catalyst were charac...
Biotechnology Amines Cellulose Catalysis Saccharum Solvents X-Ray Diffraction Temperature Spectroscopy, Fourier Transform Infrared
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Enhanced antitumor efficacy of doxorubicin-encapsulated halloysite nanotubes.

International journal of nanomedicine Dec 19, 2017
To improve the antitumor efficacy of doxorubicin (DOX) and provide novel clinical treatment of gastric cancer, halloysite nanotubes (HNTs) loaded with DOX were encapsulated by soybean phospholipid (LIP) and the formed HNTs/DOX/LIP was systematically ...
Microscopy, Electron, Transmission Aluminum Silicates Tissue Distribution Antibiotics, Antineoplastic Nanotubes Clay Humans Doxorubicin Stomach Neoplasms Thermogravimetry Drug Liberation Drug Delivery Systems Xenograft Model Antitumor Assays Animals X-Ray Diffraction Mice, Nude Phospholipids
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Innovative material containing the natural product curcumin, with enhanced antimicrobial properties for active packaging.

Materials science & engineering. C, Materials for biological applications Nov 28, 2017
Curcumin (Curc) reacts with zinc di‑iodine (ZnI) in 2:1molar ratio in the presence of an excess of a base triethylamine ((CHCH)N) in methanol (CHOH) solution towards the amorphous solid material of formula [ZnI(Curc)] (1). The complex was characteriz...
X-Ray Diffraction Biological Products Anti-Infective Agents Coordination Complexes Curcumin Microbial Sensitivity Tests Magnetic Resonance Spectroscopy Pseudomonas aeruginosa Zinc Polystyrenes Spectroscopy, Fourier Transform Infrared Drug Compounding
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Anticancer activity of biologically synthesized silver and gold nanoparticles on mouse myoblast cancer cells and their toxicity against embryonic zebrafish.

Materials science & engineering. C, Materials for biological applications Dec 23, 2016
The aim of this study was to evaluate the anticancer activity of bioinspired silver nanoparticles (AgNPs) and gold nanoparticles (AuNPs) against mouse myoblast cancer cells (CC). Both AgNPs and AuNPs were biologically synthesized using Spinacia olera...
Ethidium Photoacoustic Techniques Spinacia oleracea Silver Zebrafish Caspases Myoblasts Toxicity Tests X-Ray Diffraction Embryo, Nonmammalian Acridine Orange Cell Shape Apoptosis Cell Survival Plant Leaves Cell Line, Tumor Animals Gold Mice Antineoplastic Agents Metal Nanoparticles Staining and Labeling Plant Extracts
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Automated Phase Mapping with AgileFD and its Application to Light Absorber Discovery in the V-Mn-Nb Oxide System.

ACS combinatorial science Dec 7, 2016
Rapid construction of phase diagrams is a central tenet of combinatorial materials science with accelerated materials discovery efforts often hampered by challenges in interpreting combinatorial X-ray diffraction data sets, which we address by develo...
Vanadium Compounds Oxides X-Ray Diffraction Alloys Machine Learning Niobium Phase Transition Algorithms Manganese Compounds
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Graphene oxide as a nanocarrier for controlled release and targeted delivery of an anticancer active agent, chlorogenic acid.

Materials science & engineering. C, Materials for biological applications Dec 5, 2016
We have synthesized graphene oxide using improved Hummer's method in order to explore the potential use of the resulting graphene oxide as a nanocarrier for an active anticancer agent, chlorogenic acid (CA). The synthesized graphene oxide and chlorog...
Humans Antineoplastic Agents Spectrum Analysis, Raman Graphite Chlorogenic Acid X-Ray Diffraction Delayed-Action Preparations Hydrogen Bonding Microscopy, Electron, Transmission Oxides Spectroscopy, Fourier Transform Infrared Thermogravimetry Hydrogen-Ion Concentration Hep G2 Cells Nanocomposites Cell Survival Drug Liberation A549 Cells HeLa Cells
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Synergistic effects of proanthocyanidin, tri-calcium phosphate and fluoride on artificial root caries and dentine collagen.

Materials science & engineering. C, Materials for biological applications Nov 22, 2016
BACKGROUND: Proanthocyanidin has been shown to enhance dentine collagen stability and remineralization of artificial root caries.
Microscopy, Confocal Minerals Hydrogen-Ion Concentration Collagenases Calcium Phosphates Humans Proanthocyanidins Crystallization X-Ray Diffraction Hydroxyproline Microradiography Fluorides Dentin Drug Synergism Collagen Root Caries
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Mapping membrane activity in undiscovered peptide sequence space using machine learning.

Proceedings of the National Academy of Sciences of the United States of America Nov 14, 2016
There are some ∼1,100 known antimicrobial peptides (AMPs), which permeabilize microbial membranes but have diverse sequences. Here, we develop a support vector machine (SVM)-based classifier to investigate ⍺-helical AMPs and the interrelated nature o...
Machine Learning Anti-Bacterial Agents Support Vector Machine Antimicrobial Cationic Peptides Amino Acid Sequence Cell Membrane X-Ray Diffraction Anti-Infective Agents Peptides Microbial Sensitivity Tests Models, Theoretical
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Investigation and Manipulation of Different Analog Behaviors of Memristor as Electronic Synapse for Neuromorphic Applications.

Scientific reports Mar 14, 2016
Low-power and high-density electronic synapse is an important building block of brain-inspired systems. The recent advancement in memristor has provided an opportunity to advance electronic synapse design. However, a guideline on designing and manipu...
Electric Conductivity Long-Term Potentiation Long-Term Synaptic Depression Humans Neural Networks, Computer Brain Synapses Algorithms Photoelectron Spectroscopy Animals X-Ray Diffraction Silicon Dioxide Nerve Net Electronics Ferric Compounds
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