AIMC Topic: Acetaminophen

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Complex analyses on clinical information systems using restricted natural language querying to resolve time-event dependencies.

Journal of biomedical informatics Apr 9, 2018
PURPOSE: This paper reports on a generic framework to provide clinicians with the ability to conduct complex analyses on elaborate research topics using cascaded queries to resolve internal time-event dependencies in the research questions, as an ext...
Humans User-Computer Interface Time Factors Brain Injuries, Traumatic Liver Software Algorithms Language Data Science Liver Function Tests Acetaminophen Out-of-Hospital Cardiac Arrest Data Collection Natural Language Processing Medical Informatics Internet Body Temperature Fever Programming Languages Medical Records Systems, Computerized
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Preoperative cesarean delivery intravenous acetaminophen treatment for postoperative pain control: a randomized double-blinded placebo control trial.

American journal of obstetrics and gynecology Dec 21, 2017
BACKGROUND: The United States currently has an opioid use disorder epidemic and research evaluating ways to minimize the use of opioids postsurgery are needed. One of these options is intravenous acetaminophen. If the use of preoperative intravenous ...
Humans Young Adult Fetal Blood Adult Acetaminophen Prospective Studies Length of Stay Analgesics, Non-Narcotic Double-Blind Method Pregnancy Pain Measurement Preoperative Care Pain, Postoperative Female Analgesics, Opioid Cesarean Section Administration, Intravenous
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Correlation between degradation pathway and toxicity of acetaminophen and its by-products by using the electro-Fenton process in aqueous media.

Chemosphere Dec 21, 2016
The evolution of the degradation by-products of an acetaminophen (ACE) solution was monitored by HPLC-UV/MS and IC in parallel with its ecotoxicity (Vibrio fischeri 81.9%, Microtox screening tests) during electro-Fenton (EF) oxidation performed on ca...
Acetaminophen Aliivibrio fischeri Hydrogen Peroxide Benzoquinones Water Pollutants, Chemical Carbon Oxidation-Reduction Phenols Benzaldehydes Electrochemical Techniques Kinetics Carboxylic Acids Catalysis Electrodes Ammonium Compounds Iron Nitrates Hydroxyl Radical Benzoic Acid
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A Systematic Strategy for Screening and Application of Specific Biomarkers in Hepatotoxicity Using Metabolomics Combined With ROC Curves and SVMs.

Toxicological sciences : an official journal of the Society of Toxicology Jan 18, 2016
Current studies that evaluate toxicity based on metabolomics have primarily focused on the screening of biomarkers while largely neglecting further verification and biomarker applications. For this reason, we used drug-induced hepatotoxicity as an ex...
Acetaminophen Atorvastatin Chemical and Drug Induced Liver Injury Metabolomics Liver Chromatography, High Pressure Liquid Carbon Tetrachloride Biomarkers Sensitivity and Specificity Animals Male ROC Curve Rats, Wistar Support Vector Machine
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Artificial neural network assisted kinetic spectrophotometric technique for simultaneous determination of paracetamol and p-aminophenol in pharmaceutical samples using localized surface plasmon resonance band of silver nanoparticles.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy Dec 5, 2014
Spectrophotometric analysis method based on the combination of the principal component analysis (PCA) with the feed-forward neural network (FFNN) and the radial basis function network (RBFN) was proposed for the simultaneous determination of paraceta...
Aminophenols Microscopy, Electron, Transmission Spectrophotometry, Ultraviolet Acetaminophen Spectrophotometry Tablets Neural Networks, Computer Surface Plasmon Resonance Metal Nanoparticles Nanotechnology Limit of Detection Calibration Silver Povidone
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Comparative Analysis of Machine Learning Algorithms Evaluating the Single Nucleotide Polymorphisms of Metabolizing Enzymes with Clinical Outcomes Following Intravenous Paracetamol in Preterm Neonates with Patent Ductus Arteriosus.

Current drug metabolism Jan 1, 2024
AIMS: Pharmacogenomics has been identified to play a crucial role in determining drug response. The present study aimed to identify significant genetic predictor variables influencing the therapeutic effect of paracetamol for new indications in prete...
Algorithms Prospective Studies Female Infant, Newborn Humans Machine Learning Infant, Premature Administration, Intravenous Male Acetaminophen Polymorphism, Single Nucleotide Analgesics, Non-Narcotic Treatment Outcome Ductus Arteriosus, Patent Cytochrome P-450 Enzyme System
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Deep learning approach to unmask hidden salt effects in the era of artificial intelligence.

European heart journal Nov 7, 2023
Sodium Acetaminophen Humans Artificial Intelligence Cardiovascular Diseases Deep Learning Blood Pressure
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THE EFFECT OF TOTAL AND PARTIAL NEPHRECTOMY ON THE PHARMACOKINETICS OF INTRAVENOUS PARACETAMOL IN HUMANS.

Acta poloniae pharmaceutica May 1, 2017
Paracetamol is one of the most common analgesic and antipyretic drugs. Recently intravenous paracetamol has been widely used to treat moderate postoperative pain. Surgery is the main method of treatment of renal cancer. Total or partial nephrectomy c...
Analgesics, Non-Narcotic Nephrectomy Infusions, Intravenous Renal Elimination Adult Antipyretics Area Under Curve Chromatography, High Pressure Liquid Male Drug Monitoring Kidney Neoplasms Biological Availability Middle Aged Models, Biological Metabolic Clearance Rate Kidney Half-Life Humans Spectrophotometry, Ultraviolet Acetaminophen Female Aged Aged, 80 and over
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