BACKGROUND: Thyroid-associated orbitopathy (TAO) is an autoimmune inflammatory disorder of the orbital adipose tissue, primarily causing oxidative stress injury and tissue remodeling in the orbital connective tissue. Ferroptosis is a form of programm...
BACKGROUND: Inflammation of coronary arterial plaque is considered a key factor in the development of coronary heart disease. Early the plaque detection and timely treatment of the atherosclerosis could effectively reduce the risk of cardiovascular e...
Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
39689571
BACKGROUND: Recent studies in the field of lung cancer have emphasized the important role of body composition, particularly fatty tissue, as a prognostic factor. However, there is still a lack of practice in combining fatty tissue to discriminate ben...
OBJECTIVE: Segmentation of individual thigh muscles in MRI images is essential for monitoring neuromuscular diseases and quantifying relevant biomarkers such as fat fraction (FF). Deep learning approaches such as U-Net have demonstrated effectiveness...
PURPOSE: This paper presents a deep learning-based multi-label segmentation network that extracts a total of three separate adipose tissues and five different muscle tissues in CT slices of the third lumbar vertebra and additionally improves the segm...
Bone marrow adipose tissue is a distinct adipose subtype comprising more than 10% of fat mass in healthy humans. However, the functions and pathophysiological correlates of this tissue are unclear, and its genetic determinants remain unknown. Here, w...
To analyze radiomics features of cardiac adipose tissue in individuals with type 2 diabetes (T2DM) and non-alcoholic fatty liver disease (NAFLD), integrating relevant clinical indicators, and employing machine learning techniques to construct a preci...
Journal of cardiovascular computed tomography
39909764
BACKGROUND: Low-cost/no-cost non-contrast CT calcium scoring (CTCS) exams can provide direct evidence of coronary atherosclerosis. In this study, using features from CTCS images, we developed a novel machine learning model to predict obstructive coro...
Journal of orthopaedic surgery and research
40247403
BACKGROUND: Osteoarthritis (OA) is the leading cause of degenerative joint disease, with total joint replacement as the only definitive cure. However, no disease-modifying therapy is currently available. Inflammation and fibrosis in the infrapatellar...
Studies in health technology and informatics
40200459
Accurately assessing body fat percentage (BF%) is crucial for healthcare and fitness but is hindered by gold-standard methods that are costly and invasive. This study employs a dataset containing variables such as age, sex, Body Mass Index (BMI), and...