AIMC Topic: Adipose Tissue

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Deep learning and genome-wide association meta-analyses of bone marrow adiposity in the UK Biobank.

Nature communications
Bone marrow adipose tissue is a distinct adipose subtype comprising more than 10% of fat mass in healthy humans. However, the functions and pathophysiological correlates of this tissue are unclear, and its genetic determinants remain unknown. Here, w...

Radiomics and deep learning features of pericoronary adipose tissue on non-contrast computerized tomography for predicting non-calcified plaques.

Journal of X-ray science and technology
BACKGROUND: Inflammation of coronary arterial plaque is considered a key factor in the development of coronary heart disease. Early the plaque detection and timely treatment of the atherosclerosis could effectively reduce the risk of cardiovascular e...

Dual biomarkers CT-based deep learning model incorporating intrathoracic fat for discriminating benign and malignant pulmonary nodules in multi-center cohorts.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
BACKGROUND: Recent studies in the field of lung cancer have emphasized the important role of body composition, particularly fatty tissue, as a prognostic factor. However, there is still a lack of practice in combining fatty tissue to discriminate ben...

Identification and verification of the optimal feature genes of ferroptosis in thyroid-associated orbitopathy.

Frontiers in immunology
BACKGROUND: Thyroid-associated orbitopathy (TAO) is an autoimmune inflammatory disorder of the orbital adipose tissue, primarily causing oxidative stress injury and tissue remodeling in the orbital connective tissue. Ferroptosis is a form of programm...

Automatic segmentation of pericardial adipose tissue from cardiac MR images via semi-supervised method with difference-guided consistency.

Medical physics
BACKGROUND: Accurate and automatic segmentation of pericardial adipose tissue (PEAT) in cardiac magnetic resonance (MR) images is essential for the diagnosis and treatment of cardiovascular diseases. Precise segmentation is challenging due to high co...

Unbiased and reproducible liver MRI-PDFF estimation using a scan protocol-informed deep learning method.

European radiology
OBJECTIVE: To estimate proton density fat fraction (PDFF) from chemical shift encoded (CSE) MR images using a deep learning (DL)-based method that is precise and robust to different MR scanners and acquisition echo times (TEs).

Artificial intelligence-based analysis of lower limb muscle mass and fatty degeneration in patients with knee osteoarthritis and its correlation with Knee Society Score.

International journal of computer assisted radiology and surgery
PURPOSE: Lower-limb muscle mass reduction and fatty degeneration develop in patients with knee osteoarthritis (KOA) and could affect their symptoms, satisfaction, expectation and functional activities. The Knee Society Scoring System (KSS) includes p...

Identification of metabolism related biomarkers in obesity based on adipose bioinformatics and machine learning.

Journal of translational medicine
BACKGROUND: Obesity has emerged as a growing global public health concern over recent decades. Obesity prevalence exhibits substantial global variation, ranging from less than 5% in regions like China, Japan, and Africa to rates exceeding 75% in urba...