Positron emission tomography-computed tomography (PET-CT) is recommended for response evaluation in aggressive large B-cell lymphoma (LBCL) but cannot detect minimal residual disease (MRD). Circulating tumor DNA (ctDNA) has emerged as a promising bio...
PURPOSE: To develop an annotated fundus angiographic dataset, including fundus fluorescein angiography (FFA) and indocyanine green angiography (ICGA), and establish baseline methods for automatic report generation.
BACKGROUND: Inherited retinal diseases (IRDs) are the leading cause of blindness in young people in the UK. Despite significant improvements in genomics medicine, the diagnosis of these conditions remains challenging, and around 40% do not receive a ...
BACKGROUND: Mycosis fungoides (MF) is the most common type of cutaneous T-cell lymphoma, and early-stage MF is difficult to differentiate from erythematous inflammatory disease. With the exception of biopsy, noninvasive information such as a patient'...
The Journal of clinical endocrinology and metabolism
Oct 16, 2025
CONTEXT: Metabolic dysfunction-associated steatotic liver disease (MASLD) is an umbrella term for simple hepatic steatosis and the more severe metabolic dysfunction-associated steatohepatitis. The current reliance on liver biopsy for diagnosis and a ...
The sensory attributes of Coffea canephora beverages depend on the chemical composition of the bean, especially to the content of volatile organic compounds (VOCs). However, the relative abundance of these compounds may vary with the stage of bean ma...
BACKGROUND: Pulmonary hypertension (pH) is a malignant pulmonary circulation disease. Right heart catheterization (RHC) is the gold standard procedure for quantitative evaluation of pulmonary hemodynamics. Accurate and noninvasive quantitative evalua...
BACKGROUND: Major depressive disorder (MDD) is characterized by significant heterogeneity in treatment response, with inflammation hypothesized to play a role in its pathophysiology. Peripheral inflammatory biomarkers, such as the neutrophil-to-lymph...
BACKGROUND: Substance abuse has become a serious public health problem worldwide, and finding effective prevention and treatment strategies is undoubtedly an urgent need. This study addresses the risk factors that lead to relapse behaviors among subs...
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