AIMC Topic: Adult

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Deep Learning Model for the Differential Diagnosis of Nasal Polyps and Inverted Papilloma by CT Images: A Multicenter Study.

Academic radiology
RATIONALE AND OBJECTIVES: Nasal polyps (NP) and inverted papilloma (IP) are benign tumors within the nasal cavity, each necessitating distinct treatment approaches. Herein, we investigate the utility of a deep learning (DL) model for distinguishing b...

Prognostic Impact of Tumor Cell Nuclear Size Assessed by Artificial Intelligence in Esophageal Squamous Cell Carcinoma.

Laboratory investigation; a journal of technical methods and pathology
Tumor cell nuclear size (NS) indicates malignant potential in breast cancer; however, its clinical significance in esophageal squamous cell carcinoma (ESCC) is unknown. Artificial intelligence (AI) can quantitatively evaluate histopathological findin...

Artificial intelligence virtual assistants in primary eye care practice.

Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)
PURPOSE: To propose a novel artificial intelligence (AI)-based virtual assistant trained on tabular clinical data that can provide decision-making support in primary eye care practice and optometry education programmes.

Predicting benefit from PARP inhibitors using deep learning on H&E-stained ovarian cancer slides.

European journal of cancer (Oxford, England : 1990)
PURPOSE: Ovarian cancer patients with a Homologous Recombination Deficiency (HRD) often benefit from polyadenosine diphosphate-ribose polymerase (PARP) inhibitor maintenance therapy after response to platinum-based chemotherapy. HR status is currentl...

Comparison of population pharmacokinetic modeling and machine learning approaches for predicting voriconazole trough concentrations in critically ill patients.

International journal of antimicrobial agents
BACKGROUND: Despite the widespread use of voriconazole in antifungal treatment, its high pharmacokinetic and pharmacodynamic variability may lead to suboptimal efficacy, especially in intensive care unit (ICU) patients. Machine learning (ML), an arti...

A Self-supervised Deep Learning Model for Diagonal Sulcus Detection with Limited Labeled Data.

Neuroinformatics
Sulci are a fundamental part of brain morphology, closely linked to brain function, cognition, and behavior. Tertiary sulci, characterized as the shallowest and smallest subtype, pose a challenging task for detection. The diagonal sulcus (ds), locate...

The predictive value of heparin-binding protein for bacterial infections in patients with severe polytrauma.

PloS one
INTRODUCTION: Heparin-binding protein is an inflammatory factor with predictive value for sepsis and participates in the inflammatory response through antibacterial effects, chemotaxis, and increased vascular permeability. The role of heparin-binding...

Machine Learning Analysis of the Orbitofrontal Cortex Transcriptome of Human Opioid Users Identifies Shisa7 as a Translational Target Relevant for Heroin Seeking Leveraging a Male Rat Model.

Biological psychiatry
BACKGROUND: Identifying neurobiological targets predictive of the molecular neuropathophysiological signature of human opioid use disorder (OUD) could expedite new treatments. OUD is characterized by dysregulated cognition and goal-directed behavior ...