Hypothyroidism, a common endocrine disorder, has a high incidence in women and increases with age. Levothyroxine (LT4) is the standard therapy; however, achieving clinical and biochemical euthyroidism is challenging. Therefore, developing an accurate...
Frontiers in cellular and infection microbiology
Mar 14, 2025
PURPOSE: This study aimed to develop and validate a novel web-based calculator using machine learning algorithms to predict fragility fracture risk in People living with HIV (PLWH), who face increased morbidity and mortality from such fractures.
American journal of Alzheimer's disease and other dementias
Mar 14, 2025
White matter hyperintensity (WMH) is associated with cognitive impairment. In this study, 79 patients with WMH from hospital 1 were randomly divided into a training set (62 patients) and an internal validation set (17 patients). In addition, 29 WMH p...
BACKGROUND: Patients with chronic kidney disease (CKD) are considered the primary population at risk for post-contrast acute kidney injury (PC-AKI), yet there are few predictive tools specifically designed for this vulnerable population.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
Mar 13, 2025
BACKGROUND: Stroke is a major cause of mortality and permanent disability worldwide. Precise prediction of post-stroke mortality is essential for guiding treatment decisions and rehabilitation planning. The ability of Machine learning models to proce...
OBJECTIVE: To evaluate whether deep learning (DL) analysis of intratumor subregion based on dynamic contrast-enhanced MRI (DCE-MRI) can help predict Ki-67 expression level in breast cancer.
RATIONALE: Neoadjuvant chemotherapy (NAC) is a key element of treatment for locally advanced breast cancer (LABC). Predicting the response of NAC for patients with LABC before initiating treatment would be valuable to customize therapies and ensure t...
Cancer imaging : the official publication of the International Cancer Imaging Society
Mar 13, 2025
BACKGROUND: Accurate segmentation of pelvic and sacral tumors (PSTs) in multi-sequence magnetic resonance imaging (MRI) is essential for effective treatment and surgical planning.
OBJECTIVES: To extract intratumoral, peritumoral, and integrated intratumoral-peritumoral CT radiomic features, develop multi-source radiomic models using various machine learning algorithms to identify the optimal model, and integrate clinical facto...
BACKGROUND: The objective was to develop a biological age prediction model (NC-BA) for the Chinese population to enrich the relevant studies in this population. And to investigate the association between accelerated age and NAFLD.
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