International journal of medical informatics
Oct 1, 2025
OBJECTIVE: Half of all adult emergency department (ED) visits with a complaint of dyspnea involve acute heart failure (AHF), exacerbation of chronic obstructive pulmonary disease (eCOPD), or pneumonia, which are often misdiagnosed. We aimed to create...
BACKGROUND: Ensuring appropriate use of CT scans is critical for patient safety and resource optimization. Decision support tools and artificial intelligence (AI), such as large language models (LLMs), have the potential to improve CT referral justif...
Extrachromosomal circular DNA (eccDNA) may contribute to genomic rearrangements and tumor heterogeneity, playing a role in cancer development and progression. This study evaluates eccDNA as a biomarker for prostate cancer by characterizing its profil...
Clinical chemistry and laboratory medicine
Sep 25, 2025
OBJECTIVES: This study aimed to develop and validate a machine learning (ML) model utilizing cerebrospinal fluid (CSF) body fluid parameters from hematology analyzers to screen for malignant cells.
Clinical chemistry and laboratory medicine
Sep 25, 2025
OBJECTIVES: Machine learning (ML) models, using laboratory data, support early sepsis prediction. However, analytical bias in laboratory measurements can compromise their performance and validity in real-world settings. We aimed to evaluate how analy...
To evaluate the diagnostic value of coronary angiography-derived fractional flow reserve (FFR) and index of microcirculatory resistance (IMR) for identifying coronary functional abnormalities. This diagnostic study enrolled patients with clinically...
Vascular dementia (VaD), the second most common form of dementia, lacks reliable biomarkers for early diagnosis. Here, we integrated weighted gene co-expression network analysis (WGCNA) with machine learning to identify novel biomarkers and immune-me...
BACKGROUND: Pathological myopia (PM) has emerged as a leading cause of global visual impairment, early detection and precise grading of PM are crucial for timely intervention. The atrophy, traction and neovascularisation (ATN) system is applied to de...
AIM: To evaluate the impact of fluid volume fluctuations quantified with artificial intelligence in optical coherence tomography scans during the maintenance phase and visual outcomes at 12 and 24 months in a real-world, multicentre, national cohort ...
AIMS: The aim of this research is to diagnose polycythaemia vera (PV) disease using different machine learning (ML) algorithms with complete blood count (CBC) parameters before further investigations such as Janus kinase 2 (), erythropoietin (EPO) an...
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