CDK4/6 inhibitors in combination with endocrine therapy are widely used to treat HR+/HER2- metastatic breast cancer leading to improved progression-free survival (PFS) compared to single agent endocrine therapy. Over 300 patients receiving standard-o...
Proceedings of the National Academy of Sciences of the United States of America
Feb 26, 2025
Analyzing cardiac pulse waveforms offers valuable insights into heart health and cardiovascular disease risk, although obtaining the more informative measurements from the central aorta remains challenging due to their invasive nature and limited non...
BACKGROUND: Lumbar disc herniation (LDH) is a common cause of back and leg pain. Diagnosis relies on clinical history, physical exam, and imaging, with magnetic resonance imaging (MRI) being an important reference standard. While artificial intellige...
International journal of environmental research and public health
Feb 26, 2025
Unplanned readmission within 30 days is a major challenge both globally and in South Africa. The aim of this study was to develop a machine learning model to predict unplanned surgical and trauma readmission to a public hospital in South Africa from ...
: Liver cancer ranks among the leading causes of cancer-related mortality, necessitating the development of novel diagnostic methods. Deregulated lipid metabolism, a hallmark of hepatocarcinogenesis, offers compelling prospects for biomarker identifi...
Respiratory rate (RR) changes in the elderly can indicate serious diseases. Thus, accurate estimation of RRs for cardiopulmonary function is essential for home health monitoring systems. However, machine learning (ML) algorithm errors embedded in hea...
BACKGROUND: Alzheimer's disease (AD) is a neurodegenerative disorder that significantly impacts health care worldwide, particularly among the elderly population. The accurate classification of AD stages is essential for slowing disease progression an...
BACKGROUND: This study employed a convolutional neural network (CNN) to analyze computed tomography (CT) scans with the aim of differentiating among renal tumors according to histologic sub-type.
OBJECTIVE: This study developed and validated a stacked ensemble machine learning model to predict the risk of acute kidney injury in patients with acute pancreatitis complicated by sepsis.
BACKGROUND: The atherosclerotic cardiovascular disease (ASCVD) is associated with dementia. However, the risk factors of dementia in patients with ASCVD remain unclear, necessitating the development of accurate prediction models.
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