AIMC Topic: Animals
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Screening of Biomaterials for Stem Cell Culture Applications.
ACS biomaterials science & engineering
Jun 9, 2025
Stem cells have a considerable role to play in future biomedical breakthroughs due to their therapeutic potential. As stem cells may be studied in a variety of different applications, a "one size fits all" approach to the stem cell culture substrate ...
A novel predictive model and therapeutic potential of quercetin derivatives in chronic kidney disease progression.
Biochemical pharmacology
Jun 8, 2025
Chronic kidney disease (CKD) remains a pressing global health issue with limited therapeutic options. The loss of nephrons is a crucial pathological change driving CKD progression, influenced by diverse programmed cell death (PCD) pathways, yet the p...
Implications From the Analogous Relationship Between Evolutionary and Learning Processes.
BioEssays : news and reviews in molecular, cellular and developmental biology
Jun 8, 2025
Organismal evolution is a process of discovering better-fitting phenotypes through trial and error across generations. This iterative process resembles learning processes, an analogy recognized since the 1950s. Recognizing this parallel suggests that...
Role of tight junctions in three-dimensional mechanical model of blood-brain barrier.
Journal of biomechanics
Jun 7, 2025
The increasing prevalence of central nervous system (CNS) disorders has imposed a significant social and economic burden on healthcare systems. The blood-brain barrier (BBB) presents a major challenge for effective drug delivery to the brain, hinderi...
Codes across (life)sciences.
Bio Systems
Jun 7, 2025
The concept of "code" connotes different meanings, intentions, and formalizations. From mathematics and computer sciences to psychology and culture, the term becomes less formal, more diverse, and sometimes appears ambiguous. In biology a growing num...
Screening of bioactive compounds and deep learning-driven quality control of Angong Niuhuang pills.
Journal of ethnopharmacology
Jun 7, 2025
ETHNOPHARMACOLOGICAL RELEVANCE: Angong Niuhuang Pills (AGNHP), a famous Chinese medicine compound preparation, is widely used to treat stroke and other brain disorders. However, owing to the complexity of herbal components and diversity of production...
A machine-learning-based approach to predict early hallmarks of progressive hearing loss.
Hearing research
Jun 6, 2025
Machine learning (ML) techniques are increasingly being used to improve disease diagnosis and treatment. However, the application of these computational approaches to the early diagnosis of age-related hearing loss (ARHL), the most common sensory def...
Mice, Inbred C57BL
Predictive Value of Tests
Signal Processing, Computer-Assisted
Phenotype
Auditory Threshold
Humans
Mice
Cadherins
Male
Female
Evoked Potentials, Auditory, Brain Stem
Machine Learning
Disease Progression
Early Diagnosis
Presbycusis
Animals
Age Factors
Hearing
Disease Models, Animal
Relationship between amino acid metabolism and inflammation in coronary heart disease (Review).
International journal of molecular medicine
Jun 6, 2025
This review delves into the intricate relationship between amino acid metabolism and inflammation in coronary heart disease (CHD). Research shows that disruptions in the metabolism of arginine, glutamate, branched‑chain amino acids (BCAAs) and trypto...
Insight into microbial extracellular vesicles as key communication materials and their clinical implications for lung cancer (Review).
International journal of molecular medicine
Jun 6, 2025
The complexity of lung cancer, driven by multifactorial causes such as genetic, environmental and lifestyle factors, underscores the necessity for tailored treatment strategies informed by recent advancements. Studies highlight a significant associat...
Sleep Identification Enabled by Supervised Training Algorithms (SIESTA): An Open-Source Platform for Automatic Sleep Staging of Rodent Electrocorticographic and Electromyographic Data.
Journal of biological rhythms
Jun 6, 2025
Accurately capturing the temporal distribution of polysomnographic sleep stages is critical for the study of sleep function, regulation, and disorders in higher vertebrates. In laboratory rodents, scoring of electrocorticography (ECoG) and electromyo...
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