Neutrophils are the most abundant type of white blood cells in the immune system and play a complex and intricate regulatory role in disease progression. Their critical contribution to maintaining homeostasis through migration, activation, and progra...
Proceedings of the National Academy of Sciences of the United States of America
Oct 10, 2025
Adaptive differences in the thermal stabilities of enzyme structure and function play critical roles in establishing the thermal optima and limits of all organisms. Thus, understanding the mechanisms underlying these adaptations can yield insights in...
Computational models of neural processing in the auditory cortex usually ignore that neurons have an internal memory: they characterize their responses from simple convolutions with a finite temporal window. To circumvent this limitation, we propose ...
Wound healing is a dynamic process involving various cell types. Collecting samples from healing wounds and investigating their transcriptomics can provide deeper insights into the underlying processes. In recent years, several experiments have been ...
Type 2 diabetes mellitus (T2DM) is a severe metabolic disorder in which pancreatic injury plays a pivotal role in disease progression. Tanshinone IIA (TanIIA), a bioactive compound extracted from Salvia miltiorrhiza, has shown therapeutic potential i...
On 8 April 2024, a total solar eclipse disrupted light-dark cycles for North American birds during the lead-up to spring reproduction. Compiling more than 10,000 community observations and artificial intelligence analyses of nearly 100,000 vocalizati...
The emergence of multidrug-resistant pathogens has increased the urgency for alternative treatment options for infections like cystitis. This study focused on the green synthesis of silver nanoparticles and cysteine-conjugated silver nanoparticles ut...
Pancreatic cancer is one of the most lethal malignancies, largely due to the formidable pathophysiological barriers presented by its tumor microenvironment (TME). These include metabolic stress, such as acidosis and elevated reactive oxygen species; ...
The b-value in the diffusion magnetic resonance image(dMRI) reflects the degree to which the water molecules are affected by the magnetic field gradient pulse in the tissue, and the different b-values not only affect the image contrast but also the a...
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