AIMC Topic: Animals

Clear Filters Showing 421 to 430 of 8866 articles

Species distribution modeling to predict tsetse fly (Glossina spp.) habitat suitability in Kenya.

Parasites & vectors
BACKGROUND: African animal trypanosomosis (AAT) and human African trypanosomosis (HAT) are transmitted and spread primarily by tsetse flies (Glossina spp.) in sub-Saharan Africa. The animal disease poses significant challenges to agropastoral systems...

Integrative single-cell and machine learning approach to characterize immunogenic cell death and tumor microenvironment in LUAD.

Journal of translational medicine
BACKGROUND: Immunogenic cell death (ICD) triggers antitumor immune responses and plays a critical role in shaping the tumor microenvironment (TME). However, its specific contribution to lung adenocarcinoma (LUAD) progression and immunotherapy respons...

CCDC137 knockdown suppresses bladder cancer progression by downregulating SCD.

Journal of translational medicine
BACKGROUND: The Coiled-coil domain-containing (CCDC) family, due to its unique protein structural domain and broad involvement in diverse biological processes, has emerged as a focus in oncology research. Nevertheless, its clinical significance and f...

Route-centric ant-inspired memories enable panoramic route-following in a car-like robot.

Nature communications
Solitary foraging ants excel at route following using minimal neural resources, Robots don't. Recent biological studies proposed lateralized, nest-centric memories to explain ants' direct visual homing but did not address how ants follow curved visua...

Prediction of high-performing spleen-targeted lipid nanoparticles using a deep learning model for robust anticancer immunotherapy.

Journal of materials chemistry. B
Messenger RNA (mRNA) therapeutics hold significant potential across a wide range of medical applications. LNPs are the most clinically advanced mRNA delivery vehicles, but challenges such as off-target effects and liver accumulation limit their broad...

Frontier research on the risk of spoilage microorganisms in refrigerated marine fish: From regional to global perspectives.

International journal of food microbiology
Microbial spoilage is creating safety risks and significant wastage of refrigerated marine fish. Spoilage microorganisms possess distinct physiological adaptations that enable them to contribute to the spoilage of refrigerated marine fish, thereby co...

DIATAGeR: Triacylglycerol annotation of data-independent acquisition based lipidomics.

Analytica chimica acta
BACKGROUND: Triacylglycerols (TGs) are the most abundant lipids in the human body and the primary source of energy storage. TGs are comprised of three fatty acyls with various lengths and double bond composition, complicating structural annotation wh...

Gut microbiota dynamics in SAMP8 mice: insights from machine learning and longitudinal analysis.

Microbiology spectrum
UNLABELLED: The gut microbiota plays a crucial role in maintaining host health, and its composition is significantly influenced by aging. The SAMP8 mouse model, known for its accelerated aging process, is widely used to study age-related changes. How...

Language models reveal a complex sequence basis for adaptive convergent evolution of protein functions.

Proceedings of the National Academy of Sciences of the United States of America
Convergent evolution, or convergence, refers to repeated, independent emergences of the same trait in two or more lineages of species during evolution, often indicating functional adaptation to specific environmental factors. Many computational metho...

Neural dynamics of reversal learning in the prefrontal cortex and recurrent neural networks.

eLife
In probabilistic reversal learning, the choice option yielding reward with higher probability switches at a random trial. To perform optimally in this task, one has to accumulate evidence across trials to infer the probability that a reversal has occ...