AIMC Topic: Animals

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Evolution of Joint-Level Control for Quadrupedal Locomotion.

Artificial life
We investigate a hierarchical approach to robot control inspired by joint-level control in animals. The method combines a high-level controller, consisting of an artificial neural network (ANN), with joint-level controllers based on digital muscles. ...

Machine learning-based prediction of adverse drug effects: An example of seizure-inducing compounds.

Journal of pharmacological sciences
Various biological factors have been implicated in convulsive seizures, involving side effects of drugs. For the preclinical safety assessment of drug development, it is difficult to predict seizure-inducing side effects. Here, we introduced a machin...

EXiO-A Brain-Controlled Lower Limb Exoskeleton for Rhesus Macaques.

IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
Recent advances in the field of brain-machine interfaces (BMIs) have demonstrated enormous potential to shape the future of rehabilitation and prosthetic devices. Here, a lower-limb exoskeleton controlled by the intracortical activity of an awake beh...

Unsupervised Transfer Learning via Multi-Scale Convolutional Sparse Coding for Biomedical Applications.

IEEE transactions on pattern analysis and machine intelligence
The capabilities of (I) learning transferable knowledge across domains; and (II) fine-tuning the pre-learned base knowledge towards tasks with considerably smaller data scale are extremely important. Many of the existing transfer learning techniques ...

Prenatal Stress Exposure Generates Higher Early Survival and Smaller Size without Impacting Developmental Rate in a Pacific Salmon.

Journal of experimental zoology. Part A, Ecological genetics and physiology
Prenatal exposure to elevated glucocorticoids can act as a signal of environmental stress, resulting in modifications to offspring phenotype. While "negative" phenotypic effects (i.e., smaller size, slower growth) are often reported, recent research ...

Neuromorphic meets neuromechanics, part II: the role of fusimotor drive.

Journal of neural engineering
OBJECTIVE: We studied the fundamentals of muscle afferentation by building a Neuro-mechano-morphic system actuating a cadaveric finger. This system is a faithful implementation of the stretch reflex circuitry. It allowed the systematic exploration of...

TED: A Tolerant Edit Distance for segmentation evaluation.

Methods (San Diego, Calif.)
In this paper, we present a novel error measure to compare a computer-generated segmentation of images or volumes against ground truth. This measure, which we call Tolerant Edit Distance (TED), is motivated by two observations that we usually encount...

Metabolic changes in rat serum after administration of suberoylanilide hydroxamic acid and discriminated by SVM.

Human & experimental toxicology
Suberoylanilide hydroxamic acid (SAHA) exerts marked anticancer effects via promotion of apoptosis, cell cycle arrest, and prevention of oncogene expression. In this study, serum metabolomics and artificial intelligence recognition were used to inves...

Neuromorphic meets neuromechanics, part I: the methodology and implementation.

Journal of neural engineering
OBJECTIVE: One goal of neuromorphic engineering is to create 'realistic' robotic systems that interact with the physical world by adopting neuromechanical principles from biology. Critical to this is the methodology to implement the spinal circuitry ...