AIMC Topic: Antineoplastic Agents
Clear Filters Showing 481 to 490 of 494 articles
Identification of human flap endonuclease 1 (FEN1) inhibitors using a machine learning based consensus virtual screening.
Molecular bioSystems
Jul 25, 2017
Human Flap endonuclease1 (FEN1) is an enzyme that is indispensable for DNA replication and repair processes and inhibition of its Flap cleavage activity results in increased cellular sensitivity to DNA damaging agents (cisplatin, temozolomide, MMS, e...
The cornucopia of meaningful leads: Applying deep adversarial autoencoders for new molecule development in oncology.
Oncotarget
Feb 14, 2017
Recent advances in deep learning and specifically in generative adversarial networks have demonstrated surprising results in generating new images and videos upon request even using natural language as input. In this paper we present the first applic...
Redox-Responsive Amphipathic Dextran Nanomicelles for Solid Tumor Therapy.
Journal of biomedical nanotechnology
Dec 1, 2016
A disulfide bond containing deoxycholic acid-grafted dextran (Dex-SSDCA) was successfully prepared for drug delivery. The Dex-SSDCA polymers can self-assemble into nanomicelles at concentrations below 56 g/mL and encapsulate doxorubicin (DOX) effecti...
Diagnosis and Management of Polycythemia Vera in a Ferret ().
Comparative medicine
Dec 1, 2016
A 5-y-old female ferret (Mustela putorius furo) was evaluated for diarrhea, anorexia, and lethargy for 1 wk. Only mild dehydration was detected on physical examination. CBC analysis revealed marked erythrocytosis with an unremarkable plasma biochemis...
Quantitative ultrasound assessment of breast tumor response to chemotherapy using a multi-parameter approach.
Oncotarget
Jul 19, 2016
PURPOSE: This study demonstrated the ability of quantitative ultrasound (QUS) parameters in providing an early prediction of tumor response to neoadjuvant chemotherapy (NAC) in patients with locally advanced breast cancer (LABC).
Successful Robotic Excision and Early Chemotherapy for Primary Cardiac Lymphoma.
The Annals of thoracic surgery
Jul 1, 2016
We present a 67-year-old patient who underwent robotic excision of a mobile left ventricular mass found incidentally on echocardiography. Intraoperative findings revealed a pedunculated mass infiltrating the interventricular septum, and the results o...
A chemotherapy response classifier based on support vector machines for high-grade serous ovarian carcinoma.
Oncotarget
Jan 19, 2016
Long-term outcome of high-grade serous epithelial ovarian carcinoma (HGSOC) remains poor as a result of recurrence and the emergence of drug resistance. Almost all the patients were given the same platinum-based chemotherapy after debulking surgery e...
Disease-Free Survival
Carcinoma, Ovarian Epithelial
Drug Resistance, Neoplasm
Neoplasms, Glandular and Epithelial
Response Evaluation Criteria in Solid Tumors
Cohort Studies
Support Vector Machine
Ovarian Neoplasms
Neoplasm Recurrence, Local
Decision Support Techniques
Female
Middle Aged
Antineoplastic Agents
Humans
Everolimus in heavily pretreated metastatic breast cancer: Is real world experience different?
Indian journal of cancer
Jan 1, 2016
BACKGROUND: Drugs targeting mammalian target of rapamycin signaling pathway have been recently approved for treatment of hormone receptor (HR) positive metastatic breast cancer (MBC). However, there is lack of real world data from India on the use of...
Effect of Transtympanic Injection of Melatonin on Cisplatin-Induced Ototoxicity.
The journal of international advanced otology
Dec 1, 2015
OBJECTIVE: Cisplatin is a chemotherapeutic agent that is widely used in cancer treatment. Numerous side effects have been detected, one of which is ototoxicity. Melatonin, a product of the pineal gland, has a neuroendocrinoimmunological role in verte...
[The Safety and Feasibility of Conversion Surgery for Initially Unresectable Pancreatic Cancer].
Gan to kagaku ryoho. Cancer & chemotherapy
Nov 1, 2015
BACKGROUND: By remarkable progress of chemotherapy for pancreatic cancer, we sometimes achieve resection of initially unresectable pancreatic cancer after chemotherapy. Otherwise, the safety and feasibility of radical pancreatic resection after chemo...
Don't Miss the Future of Medicine
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.
Subscribe NowPopular Topics
- Machine Learning 31137
- Neural Networks, Computer 29769
- Algorithms 26908
- Deep Learning 26418
- Artificial Intelligence 24354
- Robotics 13322
- Image Processing, Computer-Assisted 9552
- Retrospective Studies 9136
- Magnetic Resonance Imaging 6198
- Reproducibility of Results 5602
- Tomography, X-Ray Computed 4778
- Support Vector Machine 4695
- Computational Biology 4246
- Brain 4056
- Computer Simulation 3887
Recent Journals
- Scientific reports 6082
- Sensors (Basel, Switzerland) 4794
- PloS one 4044
- Neural networks : the official journal of the International Neural Network Society 2930
- Computational intelligence and neuroscience 1931
- Computers in biology and medicine 1868
- Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 1686
- Studies in health technology and informatics 1278
- IEEE journal of biomedical and health informatics 1137
- Journal of chemical information and modeling 1006
- Nature communications 959
- Computer methods and programs in biomedicine 883
- Bioinformatics (Oxford, England) 862
- Briefings in bioinformatics 853
- IEEE transactions on neural networks and learning systems 829