The widespread exposure of acute myocardial infarction globally demands an ultrasensitive, rapid, and cost-effective biosensor for troponin-I and T in a dynamic concentration range. Traditionally, the saturation of sensor response limits accurate pre...
BACKGROUND AND OBJECTIVES: Among the participants of Alzheimer disease (AD) treatment trials, 40% do not show cognitive decline over 80 weeks of follow-up. Identifying and excluding these individuals can increase power to detect treatment effects. We...
Preterm birth (PTB), defined as delivery before 37 weeks, affects 15 million infants annually, accounting for 11% of live births and over 35% of neonatal deaths. While advanced maternal age (≥ 35 years) is a known risk factor, PTB risk in women under...
BACKGROUND: Individuals with anxious-depressed (AD) symptoms have more severe mood disorders and cognitive impairment than those with non-anxious depression (NAD) symptoms. Therefore, it is important to clarify the underlying neurophysiology of these...
Adipogenesis is intricately linked to the onset and progression of muscle aging; however, the relevant biomarkers remain unclear. This study sought to identify key genes associated with adipogenesis in the context of muscle aging. Firstly, gene expre...
BACKGROUND: Ischemic stroke (IS) is one of the most common causes of disability in adults worldwide. This study aimed to identify key genes related to the inflammatory response to provide insights into the mechanisms and management of IS.
INTRODUCTION: Epigenetic biomarkers are molecular indicators of epigenetic changes, and some studies have suggested that these biomarkers have predictive power for disease risk. This study aims to analyze the relationship between 30 epigenetic biomar...
INTRODUCTION: The landscape of early drug discovery is rapidly evolving, fueled by significant advancements in artificial intelligence (AI) and machine learning (ML), which are transforming the way drugs are discovered. As traditional drug discovery ...
Spinal cord stimulation (SCS) is a well-accepted therapy for refractory chronic pain. However, predicting responders remain a challenge due to a lack of objective pain biomarkers. The present study applies machine learning to predict which patients w...
BACKGROUND: Diabetic cardiomyopathy (DC) is a serious complication in patients with type 1 diabetes mellitus and has become a growing public health problem worldwide. There is evidence that endoplasmic reticulum stress (ERS) is involved in the pathog...
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.