BACKGROUND: Childhood obesity poses a significant risk to bone health, but the impact of insulin resistance (IR) on bone metabolism in prepubertal children, as assessed by the triglyceride-glucose (TyG) index, remains underexplored. Bone turnover mar...
BACKGROUND: Tuberculous pleural effusion (TPE) is a prevalent tuberculosis complication, with diagnosis presenting considerable challenges. Timely and precise identification of TPE is vital for effective patient management and prognosis, yet existing...
Frontiers in cellular and infection microbiology
Jan 1, 2025
Tuberculosis (TB) remains a global health challenge, with timely and accurate diagnosis being critical for effective disease management and control. Recent advancements in the field of TB diagnostics have focused on the identification and utilization...
INTRODUCTION: Dementia is a neurodegenerative syndrome marked by the accumulation of disease-specific proteins and immune dysregulation, including autoimmune mechanisms involving autoantibodies. Current diagnostic methods are often invasive, time-con...
BACKGROUND: Psoriasis and Crohn's disease (CD) are chronic inflammatory diseases that involve complex immune-mediated mechanisms. Despite clinical overlap and shared genetic predispositions, the molecular pathways connecting these diseases remain inc...
BACKGROUND: Pediatric chronic rhinosinusitis (CRS) is a common chronic inflammatory disease with a high recurrence rate after surgery. This study aimed to construct and validate a machine learning-based predictive model to predict the risk of postope...
Kawasaki disease (KD) is an acute vasculitis that primarily affects children under five and is a leading cause of acquired heart disease in this age group. Despite the standard treatment with intravenous immunoglobulin (IVIG), approximately 10-20% of...
Depression presents a significant challenge to global mental health, often intertwined with factors including oxidative stress. Although the precise relationship with mitochondrial pathways remains elusive, recent advances in machine learning present...
Fungal pathogens significantly impact human health, agriculture, and ecosystems, with infections leading to high morbidity and mortality, especially among immunocompromised individuals. The increasing prevalence of antifungal resistance (AFR) exacerb...
European review for medical and pharmacological sciences
Jan 1, 2025
OBJECTIVE: Chronic rhinosinusitis (CRS) has traditionally been classified phenotypically according to the presence (CRSwNP) or absence (CRSsNP) of nasal polyps. However, the phenotypic dichotomy does not represent the complexity of the disease. Curre...
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