AIMC Topic: Bone Neoplasms

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Sarcoma classification by DNA methylation profiling.

Nature communications Jan 21, 2021
Sarcomas are malignant soft tissue and bone tumours affecting adults, adolescents and children. They represent a morphologically heterogeneous class of tumours and some entities lack defining histopathological features. Therefore, the diagnosis of sa...
Humans Machine Learning Algorithms Bone Neoplasms DNA Copy Number Variations Internet Sarcoma Soft Tissue Neoplasms Reproducibility of Results Sensitivity and Specificity Cohort Studies DNA Methylation
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Deep learning-based classification of primary bone tumors on radiographs: A preliminary study.

EBioMedicine Nov 22, 2020
BACKGROUND: To develop a deep learning model to classify primary bone tumors from preoperative radiographs and compare performance with radiologists.
Neoplasm Grading ROC Curve Image Processing, Computer-Assisted Bone Neoplasms Female Radiography Reproducibility of Results Young Adult Adult Humans Deep Learning Adolescent Male Child Middle Aged
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Deep neural network based artificial intelligence assisted diagnosis of bone scintigraphy for cancer bone metastasis.

Scientific reports Oct 12, 2020
Bone scintigraphy (BS) is one of the most frequently utilized diagnostic techniques in detecting cancer bone metastasis, and it occupies an enormous workload for nuclear medicine physicians. So, we aimed to architecture an automatic image interpretin...
Bone Neoplasms Bone and Bones Radionuclide Imaging Male Middle Aged Diagnosis, Computer-Assisted Image Processing, Computer-Assisted Humans Neural Networks, Computer Aged Adult Sensitivity and Specificity Artificial Intelligence Female
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Effectiveness of Radiofrequency Ablation in the Treatment of Painful Osseous Metastases: A Correlation Meta-Analysis with Machine Learning Cluster Identification.

Journal of vascular and interventional radiology : JVIR Oct 1, 2020
A systematic review and meta-analysis of pain response after radiofrequency (RF) ablation over time for osseous metastases was conducted in 2019. Analysis used a random-effects model with GOSH plots and meta-regression. Fourteen studies comprising 42...
Humans Male Middle Aged Quality of Life Time Factors Treatment Outcome Machine Learning Female Aged Adult Palliative Care Radiofrequency Ablation Cementoplasty Cluster Analysis Bone Neoplasms Pain Measurement Pain
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An immune-related gene signature for determining Ewing sarcoma prognosis based on machine learning.

Journal of cancer research and clinical oncology Sep 23, 2020
PURPOSE: Ewing sarcoma (ES) is one of the most common malignant bone tumors in children and adolescents. The immune microenvironment plays an important role in the development of ES. Here, we developed an optimal signature for determining ES patient ...
Bone Neoplasms Sarcoma, Ewing Adolescent Gene Expression Regulation, Neoplastic Follow-Up Studies Lymphocytes, Tumor-Infiltrating Tumor Microenvironment Biomarkers, Tumor Male Gene Expression Profiling Prognosis Female Humans Survival Rate Machine Learning
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Development of Convolutional Neural Networks to identify bone metastasis for prostate cancer patients in bone scintigraphy.

Annals of nuclear medicine Aug 24, 2020
OBJECTIVE: The main aim of this work is to build a robust Convolutional Neural Network (CNN) algorithm that efficiently and quickly classifies bone scintigraphy images, by determining the presence or absence of prostate cancer metastasis.
Prostatic Neoplasms Image Interpretation, Computer-Assisted Bone and Bones Radionuclide Imaging Neural Networks, Computer Humans Retrospective Studies Male Bone Neoplasms
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Machine Learning Algorithms for Early Detection of Bone Metastases in an Experimental Rat Model.

Journal of visualized experiments : JoVE Aug 16, 2020
Machine learning (ML) algorithms permit the integration of different features into a model to perform classification or regression tasks with an accuracy exceeding its constituents. This protocol describes the development of an ML algorithm to predic...
Neural Networks, Computer Machine Learning Female Sensitivity and Specificity Rats Magnetic Resonance Imaging Early Detection of Cancer Animals Disease Models, Animal Humans Bone Neoplasms Image Processing, Computer-Assisted Positron Emission Tomography Computed Tomography
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Bone metastasis classification using whole body images from prostate cancer patients based on convolutional neural networks application.

PloS one Aug 14, 2020
Bone metastasis is one of the most frequent diseases in prostate cancer; scintigraphy imaging is particularly important for the clinical diagnosis of bone metastasis. Up to date, minimal research has been conducted regarding the application of machin...
Image Interpretation, Computer-Assisted Radionuclide Imaging Whole Body Imaging Male Humans Diagnosis, Computer-Assisted Neural Networks, Computer Bone Neoplasms Machine Learning Prostatic Neoplasms Software
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Image based cellular contractile force evaluation with small-world network inspired CNN: SW-UNet.

Biochemical and biophysical research communications Jul 7, 2020
We propose an image based cellular contractile force evaluation method using a machine learning technique. We use a special substrate that exhibits wrinkles when cells grab the substrate and contract, and the wrinkles can be used to visualize the for...
Mutation Microscopy Humans Proto-Oncogene Proteins p21(ras) Neural Networks, Computer Cell Line, Tumor Machine Learning Image Processing, Computer-Assisted Algorithms Osteosarcoma Biomechanical Phenomena Bone Neoplasms
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An Artificial Intelligence Model for Predicting 1-Year Survival of Bone Metastases in Non-Small-Cell Lung Cancer Patients Based on XGBoost Algorithm.

BioMed research international Jun 27, 2020
Non-small-cell lung cancer (NSCLC) patients often develop bone metastases (BM), and the overall survival for these patients is usually perishing. However, a model with high accuracy for predicting the survival of NSCLC with BM is still lacking. Here,...
Lung Neoplasms Logistic Models Nomograms Carcinoma, Non-Small-Cell Lung Reproducibility of Results Aged Male ROC Curve Humans Bone Neoplasms Models, Biological Artificial Intelligence Survival Analysis Algorithms Multivariate Analysis Prognosis Female
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