AIMC Topic: Cerebral Cortex

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Optimizing Machine Learning Methods to Improve Predictive Models of Alzheimer's Disease.

Journal of Alzheimer's disease : JAD
BACKGROUND: Predicting clinical course of cognitive decline can boost clinical trials' power and improve our clinical decision-making. Machine learning (ML) algorithms are specifically designed for the purpose of prediction; however. identifying opti...

Neural activity reveals interactions between episodic and semantic memory systems during retrieval.

Journal of experimental psychology. General
Whereas numerous findings support a distinction between episodic and semantic memory, it is now widely acknowledged that these two forms of memory interact during both encoding and retrieval. The precise nature of this interaction, however, remains p...

Working Memory: Delay Activity, Yes! Persistent Activity? Maybe Not.

The Journal of neuroscience : the official journal of the Society for Neuroscience
Persistent spiking has been thought to underlie working memory (WM). However, virtually all of the evidence for this comes from studies that averaged spiking across time and across trials, which masks the details. On single trials, activity often occ...

SPICODYN: A Toolbox for the Analysis of Neuronal Network Dynamics and Connectivity from Multi-Site Spike Signal Recordings.

Neuroinformatics
We implemented an automated and efficient open-source software for the analysis of multi-site neuronal spike signals. The software package, named SPICODYN, has been developed as a standalone windows GUI application, using C# programming language with...

A pilot study on the optimal speeds for passive wrist movements by a rehabilitation robot of stroke patients: A functional NIRS study.

IEEE ... International Conference on Rehabilitation Robotics : [proceedings]
The optimal conditions inducing proper brain activation during performance of rehabilitation robots should be examined to enhance the efficiency of robot rehabilitation based on the concept of brain plasticity. In this study, we attempted to investig...

Collection of Simulated Data from a Thalamocortical Network Model.

Neuroinformatics
A major challenge in experimental data analysis is the validation of analytical methods in a fully controlled scenario where the justification of the interpretation can be made directly and not just by plausibility. In some sciences, this could be a ...

Learning-based subject-specific estimation of dynamic maps of cortical morphology at missing time points in longitudinal infant studies.

Human brain mapping
Longitudinal neuroimaging analysis of the dynamic brain development in infants has received increasing attention recently. Many studies expect a complete longitudinal dataset in order to accurately chart the brain developmental trajectories. However,...

Synaptic Mechanisms of Memory Consolidation during Sleep Slow Oscillations.

The Journal of neuroscience : the official journal of the Society for Neuroscience
UNLABELLED: Sleep is critical for regulation of synaptic efficacy, memories, and learning. However, the underlying mechanisms of how sleep rhythms contribute to consolidating memories acquired during wakefulness remain unclear. Here we studied the ro...

Best facilitated cortical activation during different stepping, treadmill, and robot-assisted walking training paradigms and speeds: A functional near-infrared spectroscopy neuroimaging study.

NeuroRehabilitation
BACKGROUND: Robot-assisted and treadmill-gait training are promising neurorehabilitation techniques, with advantages over conventional gait training, but the neural substrates underpinning locomotor control remain unknown particularly during differen...

Electroencephalographic markers of robot-aided therapy in stroke patients for the evaluation of upper limb rehabilitation.

International journal of rehabilitation research. Internationale Zeitschrift fur Rehabilitationsforschung. Revue internationale de recherches de readaptation
Stroke is the leading cause of permanent disability in developed countries; its effects may include sensory, motor, and cognitive impairment as well as a reduced ability to perform self-care and participate in social and community activities. A numbe...