AIMC Topic: Disease Models, Animal
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An Implantable Extracardiac Soft Robotic Device for the Failing Heart: Mechanical Coupling and Synchronization.
Soft robotics
May 30, 2017
Soft robotic devices have significant potential for medical device applications that warrant safe synergistic interaction with humans. This article describes the optimization of an implantable soft robotic system for heart failure whereby soft actuat...
An Intracardiac Soft Robotic Device for Augmentation of Blood Ejection from the Failing Right Ventricle.
Annals of biomedical engineering
May 16, 2017
We introduce an implantable intracardiac soft robotic right ventricular ejection device (RVED) for dynamic approximation of the right ventricular (RV) free wall and the interventricular septum (IVS) in synchrony with the cardiac cycle to augment bloo...
Cooperative robot assistant for vitreoretinal microsurgery: development of the RVRMS and feasibility studies in an animal model.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie
Apr 8, 2017
PURPOSE: The purpose of the study was to describe the development of a robotic aided surgical system named RVRMS (robotic vitreous retinal microsurgery system) and to evaluate the capability for using it to perform vitreoretinal surgery.
Robot-assisted retinal vein cannulation in an in vivo porcine retinal vein occlusion model.
Acta ophthalmologica
Jan 13, 2017
PURPOSE: To evaluate the feasibility of robot-assisted retinal vein cannulation for retinal vein occlusion.
Preparation of arginine-glycine-aspartic acid-modified biopolymeric nanoparticles containing epigalloccatechin-3-gallate for targeting vascular endothelial cells to inhibit corneal neovascularization.
International journal of nanomedicine
Dec 30, 2016
Neovascularization (NV) of the cornea can disrupt visual function, causing ocular diseases, including blindness. Therefore, treatment of corneal NV has a high public health impact. Epigalloccatechin-3-gallate (EGCG), presenting antiangiogenesis effec...
Catechin
Molecular Targeted Therapy
Oligopeptides
Integrin alphaVbeta3
Corneal Neovascularization
Eye Burns
Burns, Chemical
Human Umbilical Vein Endothelial Cells
Humans
Disease Models, Animal
Ophthalmic Solutions
Animals
Mice, Inbred C57BL
Hyaluronic Acid
Nanoparticles
Cell Survival
Angiogenesis Inhibitors
The injury of serotonin on intestinal epithelium cell renewal of weaned diarrhoea mice.
European journal of histochemistry : EJH
Dec 28, 2016
Diarrhoea is a common cause of death in children and weaned animals. Recent research has found that serotonin (5-HT) in the gastrointestinal tract plays an important role in regulating growth and the maintenance of mucosa, which protect against diarr...
Role of Antioxidants in Horse Serum-mediated Vasculitis in Swine: Potential Relevance to Early Treatment in Mitigation of Coronary Arteritis in Kawasaki Disease.
Pediatrics and neonatology
Dec 18, 2016
BACKGROUND: Horse serum-induced immune complex coronary vasculitis in swine is the first experimental model to mimic most of the pictures of Kawasaki disease. Immune complex mechanism has been implicated as one of the possible mechanisms in the patho...
Tenascin-C Prevents Articular Cartilage Degeneration in Murine Osteoarthritis Models.
Cartilage
Dec 4, 2016
Objective The objective of this study was to determine whether intra-articular injections of tenascin-C (TNC) could prevent cartilage damage in murine models of osteoarthritis (OA). Design Fluorescently labeled TNC was injected into knee joints and i...
Robust Wavelet Stabilized 'Footprints of Uncertainty' for Fuzzy System Classifiers to Automatically Detect Sharp Waves in the EEG after Hypoxia Ischemia.
International journal of neural systems
Aug 18, 2016
Currently, there are no developed methods to detect sharp wave transients that exist in the latent phase after hypoxia-ischemia (HI) in the electroencephalogram (EEG) in order to determine if these micro-scale transients are potential biomarkers of H...
Machine Learning Model Analysis and Data Visualization with Small Molecules Tested in a Mouse Model of Mycobacterium tuberculosis Infection (2014-2015).
Journal of chemical information and modeling
Jul 1, 2016
The renewed urgency to develop new treatments for Mycobacterium tuberculosis (Mtb) infection has resulted in large-scale phenotypic screening and thousands of new active compounds in vitro. The next challenge is to identify candidates to pursue in a ...
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