AIMC Topic: Disease Progression

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Screening of Alzheimer's disease by facial complexion using artificial intelligence.

Aging
Despite the increasing incidence and high morbidity associated with dementia, a simple, non-invasive, and inexpensive method of screening for dementia is yet to be discovered. This study aimed to examine whether artificial intelligence (AI) could dis...

An Interpretable Machine Learning Survival Model for Predicting Long-term Kidney Outcomes in IgA Nephropathy.

AMIA ... Annual Symposium proceedings. AMIA Symposium
IgA nephropathy (IgAN) is common worldwide and has heterogeneous phenotypes. Predicting long-term outcomes is important for clinical decision-making. As right-censored patients become common during the long-term follow-up, either excluding these pati...

Cognitive and MRI trajectories for prediction of Alzheimer's disease.

Scientific reports
The concept of Mild Cognitive Impairment (MCI) is used to describe the early stages of Alzheimer's disease (AD), and identification and treatment before further decline is an important clinical task. We selected longitudinal data from the ADNI databa...

Current cancer driver variant predictors learn to recognize driver genes instead of functional variants.

BMC biology
BACKGROUND: Identifying variants that drive tumor progression (driver variants) and distinguishing these from variants that are a byproduct of the uncontrolled cell growth in cancer (passenger variants) is a crucial step for understanding tumorigenes...

Modular machine learning for Alzheimer's disease classification from retinal vasculature.

Scientific reports
Alzheimer's disease is the leading cause of dementia. The long progression period in Alzheimer's disease provides a possibility for patients to get early treatment by having routine screenings. However, current clinical diagnostic imaging tools do no...

Recurrent disease progression networks for modelling risk trajectory of heart failure.

PloS one
MOTIVATION: Recurrent neural networks (RNN) are powerful frameworks to model medical time series records. Recent studies showed improved accuracy of predicting future medical events (e.g., readmission, mortality) by leveraging large amount of high-di...

Deep learning detection of informative features in tau PET for Alzheimer's disease classification.

BMC bioinformatics
BACKGROUND: Alzheimer's disease (AD) is the most common type of dementia, typically characterized by memory loss followed by progressive cognitive decline and functional impairment. Many clinical trials of potential therapies for AD have failed, and ...

Assessing Glaucoma Progression Using Machine Learning Trained on Longitudinal Visual Field and Clinical Data.

Ophthalmology
PURPOSE: Rule-based approaches to determining glaucoma progression from visual fields (VFs) alone are discordant and have tradeoffs. To detect better when glaucoma progression is occurring, we used a longitudinal data set of merged VF and clinical da...